MAN2A1-DT

Summary

MAN2A1-DT (MAN2A1 divergent transcript, HGNC:54821) is a long non-coding RNA gene on chromosome 5q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54821
Approved symbol	MAN2A1-DT
Name	MAN2A1 divergent transcript
Location	5q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000271849
Ensembl biotype	lncRNA
Entrez	124901041
RNAcentral	URS0002336B24 — lncRNA, 3299 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000606424

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606424 — 1 exons

Exon	Start	End
ENSE00003695611	109687802	109688329

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 75.28.

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
Brodmann (1909) area 9	UBERON:0013540	75.28	gold quality
prefrontal cortex	UBERON:0000451	74.82	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	74.50	gold quality
frontal cortex	UBERON:0001870	74.10	gold quality
right frontal lobe	UBERON:0002810	73.75	gold quality
cerebral cortex	UBERON:0000956	72.77	gold quality
superior frontal gyrus	UBERON:0002661	72.18	gold quality
anterior cingulate cortex	UBERON:0009835	72.10	gold quality
skeletal muscle tissue	UBERON:0001134	71.34	gold quality
gastrocnemius	UBERON:0001388	70.40	gold quality
muscle of leg	UBERON:0001383	70.04	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.80	gold quality
smooth muscle tissue	UBERON:0001135	69.39	gold quality
cortical plate	UBERON:0005343	69.00	gold quality
mucosa of stomach	UBERON:0001199	67.88	gold quality
primary visual cortex	UBERON:0002436	67.51	gold quality
Ammon’s horn	UBERON:0001954	67.00	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	66.80	gold quality
granulocyte	CL:0000094	66.37	gold quality
amygdala	UBERON:0001876	66.01	gold quality
temporal lobe	UBERON:0001871	65.94	gold quality
bone marrow	UBERON:0002371	65.90	gold quality
gall bladder	UBERON:0002110	65.77	gold quality
right lobe of liver	UBERON:0001114	65.72	gold quality
liver	UBERON:0002107	65.63	gold quality
substantia nigra	UBERON:0002038	65.29	gold quality
brain	UBERON:0000955	65.16	gold quality
islet of Langerhans	UBERON:0000006	64.38	gold quality
thoracic aorta	UBERON:0001515	64.20	gold quality
ascending aorta	UBERON:0001496	64.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.