MANEA-DT

Summary

MANEA-DT (MANEA divergent transcript, HGNC:43732) is a long non-coding RNA gene on chromosome 6q16.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43732
Approved symbol	MANEA-DT
Name	MANEA divergent transcript
Location	6q16.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261366
Ensembl biotype	lncRNA
Entrez	101927288
RNAcentral	URS0000759F6C — lncRNA, 2280 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000564541, ENST00000791249, ENST00000791250, ENST00000791251, ENST00000791252, ENST00000791253, ENST00000791254

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000564541 — 1 exons

Exon	Start	End
ENSE00002577955	95575183	95577450

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 81.27.

FANTOM5 (CAGE): breadth broad, TPM avg 1.2526 / max 31.6554, expressed in 596 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
74767	1.2526	596

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.27	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.03	gold quality
bone marrow cell	CL:0002092	72.35	gold quality
cortical plate	UBERON:0005343	72.24	gold quality
popliteal artery	UBERON:0002250	68.14	gold quality
tibial artery	UBERON:0007610	68.09	gold quality
calcaneal tendon	UBERON:0003701	67.89	gold quality
lymph node	UBERON:0000029	67.05	gold quality
left coronary artery	UBERON:0001626	66.49	gold quality
vermiform appendix	UBERON:0001154	65.93	gold quality
descending thoracic aorta	UBERON:0002345	65.57	gold quality
colonic epithelium	UBERON:0000397	65.44	silver quality
ganglionic eminence	UBERON:0004023	65.32	gold quality
left ovary	UBERON:0002119	65.29	gold quality
ovary	UBERON:0000992	64.64	gold quality
right ovary	UBERON:0002118	64.53	gold quality
ventricular zone	UBERON:0003053	64.25	gold quality
endometrium	UBERON:0001295	64.24	gold quality
vagina	UBERON:0000996	64.18	gold quality
ascending aorta	UBERON:0001496	64.16	gold quality
thoracic aorta	UBERON:0001515	64.08	gold quality
tonsil	UBERON:0002372	63.99	gold quality
tibial nerve	UBERON:0001323	63.48	gold quality
bone marrow	UBERON:0002371	63.39	gold quality
ectocervix	UBERON:0012249	63.32	gold quality
monocyte	CL:0000576	63.25	gold quality
uterine cervix	UBERON:0000002	63.25	gold quality
body of uterus	UBERON:0009853	63.19	gold quality
right coronary artery	UBERON:0001625	63.15	gold quality
endocervix	UBERON:0000458	62.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.