MAP2K5-DT

Summary

MAP2K5-DT (MAP2K5 divergent transcript, HGNC:55261) is a long non-coding RNA gene on chromosome 15q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55261
Approved symbol	MAP2K5-DT
Name	MAP2K5 divergent transcript
Location	15q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000270964
Ensembl biotype	lncRNA
Entrez	118732298
RNAcentral	URS00026A28A5 — lncRNA, 1563 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000604760

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000604760 — 1 exons

Exon	Start	End
ENSE00003534616	67541072	67542604

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 84.23.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.23	gold quality
bone marrow cell	CL:0002092	69.33	silver quality
mucosa of transverse colon	UBERON:0004991	68.13	gold quality
islet of Langerhans	UBERON:0000006	67.97	gold quality
rectum	UBERON:0001052	65.34	gold quality
ganglionic eminence	UBERON:0004023	64.70	gold quality
right adrenal gland	UBERON:0001233	64.35	gold quality
duodenum	UBERON:0002114	64.35	gold quality
right adrenal gland cortex	UBERON:0035827	63.86	gold quality
left adrenal gland	UBERON:0001234	63.79	gold quality
left adrenal gland cortex	UBERON:0035825	63.67	gold quality
pancreas	UBERON:0001264	63.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.32	gold quality
skeletal muscle tissue	UBERON:0001134	63.11	gold quality
adrenal gland	UBERON:0002369	62.94	gold quality
ventricular zone	UBERON:0003053	62.72	gold quality
metanephros cortex	UBERON:0010533	62.48	gold quality
transverse colon	UBERON:0001157	62.14	gold quality
sural nerve	UBERON:0015488	61.86	silver quality
right uterine tube	UBERON:0001302	61.53	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.25	gold quality
liver	UBERON:0002107	61.08	gold quality
cortical plate	UBERON:0005343	60.99	silver quality
body of pancreas	UBERON:0001150	60.82	gold quality
cortex of kidney	UBERON:0001225	60.66	gold quality
right lobe of liver	UBERON:0001114	60.43	gold quality
muscle of leg	UBERON:0001383	59.64	gold quality
small intestine	UBERON:0002108	59.33	gold quality
leukocyte	CL:0000738	59.11	gold quality
gastrocnemius	UBERON:0001388	59.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.