MAP2K6-AS1

Summary

MAP2K6-AS1 (MAP2K6 antisense RNA 1, HGNC:58588) is a long non-coding RNA gene on chromosome 17q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58588
Approved symbol	MAP2K6-AS1
Name	MAP2K6 antisense RNA 1
Location	17q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267653
Ensembl biotype	lncRNA
Entrez	105371880

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000585537, ENST00000759739, ENST00000759740

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000585537 — 3 exons

Exon	Start	End
ENSE00002822127	69501699	69501755
ENSE00002868489	69477139	69477550
ENSE00002899475	69485235	69485349

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 90.25.

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
subcutaneous adipose tissue	UBERON:0002190	90.25	gold quality
adipose tissue	UBERON:0001013	89.19	gold quality
omental fat pad	UBERON:0010414	87.74	gold quality
left uterine tube	UBERON:0001303	84.26	gold quality
tibial nerve	UBERON:0001323	84.07	gold quality
thoracic mammary gland	UBERON:0005200	82.29	gold quality
apex of heart	UBERON:0002098	81.45	gold quality
left coronary artery	UBERON:0001626	78.59	gold quality
right atrium auricular region	UBERON:0006631	77.50	gold quality
gastrocnemius	UBERON:0001388	77.20	gold quality
popliteal artery	UBERON:0002250	76.72	gold quality
tibial artery	UBERON:0007610	76.70	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.68	gold quality
heart	UBERON:0000948	76.51	gold quality
heart left ventricle	UBERON:0002084	76.42	gold quality
muscle of leg	UBERON:0001383	75.65	gold quality
hindlimb stylopod muscle	UBERON:0004252	75.53	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	73.50	gold quality
lymph node	UBERON:0000029	71.95	gold quality
right lobe of thyroid gland	UBERON:0001119	71.90	gold quality
lower esophagus muscularis layer	UBERON:0035833	71.86	gold quality
lower esophagus	UBERON:0013473	71.72	gold quality
mucosa of stomach	UBERON:0001199	71.43	gold quality
urinary bladder	UBERON:0001255	71.17	gold quality
ectocervix	UBERON:0012249	71.11	gold quality
skeletal muscle tissue	UBERON:0001134	71.02	gold quality
fallopian tube	UBERON:0003889	70.73	gold quality
left lobe of thyroid gland	UBERON:0001120	69.59	gold quality
descending thoracic aorta	UBERON:0002345	69.03	gold quality
muscle tissue	UBERON:0002385	68.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	15.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.