MAP3K1-AS1

Summary

MAP3K1-AS1 (MAP3K1 antisense RNA 1, HGNC:40357) is a long non-coding RNA gene on chromosome 5q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40357
Approved symbol	MAP3K1-AS1
Name	MAP3K1 antisense RNA 1
Location	5q11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237705
Ensembl biotype	lncRNA
Entrez	144699900

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000415589

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415589 — 4 exons

Exon	Start	End
ENSE00001613458	56851990	56852074
ENSE00001615891	56842016	56842213
ENSE00001632580	56862074	56862164
ENSE00001637921	56859669	56859913

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 85.32.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.32	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.09	silver quality
monocyte	CL:0000576	74.89	gold quality
leukocyte	CL:0000738	74.45	gold quality
bone marrow cell	CL:0002092	73.19	gold quality
colonic epithelium	UBERON:0000397	71.99	gold quality
sural nerve	UBERON:0015488	68.50	gold quality
skeletal muscle tissue	UBERON:0001134	68.42	gold quality
bone marrow	UBERON:0002371	68.22	gold quality
calcaneal tendon	UBERON:0003701	68.20	gold quality
adrenal tissue	UBERON:0018303	65.74	gold quality
corpus callosum	UBERON:0002336	65.35	gold quality
blood	UBERON:0000178	61.88	gold quality
skin of abdomen	UBERON:0001416	59.56	gold quality
zone of skin	UBERON:0000014	58.83	gold quality
skin of leg	UBERON:0001511	58.25	gold quality
kidney	UBERON:0002113	57.66	gold quality
liver	UBERON:0002107	57.58	gold quality
lymph node	UBERON:0000029	57.05	gold quality
endometrium	UBERON:0001295	56.13	gold quality
lung	UBERON:0002048	54.19	gold quality
placenta	UBERON:0001987	53.39	gold quality
thoracic mammary gland	UBERON:0005200	52.85	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.34	gold quality
tonsil	UBERON:0002372	52.15	gold quality
uterine cervix	UBERON:0000002	52.08	gold quality
prefrontal cortex	UBERON:0000451	51.80	gold quality
vagina	UBERON:0000996	51.71	gold quality
adult mammalian kidney	UBERON:0000082	51.55	gold quality
muscle of leg	UBERON:0001383	51.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.