MAP3K14-AS1

Summary

MAP3K14-AS1 (MAP3K14 antisense RNA 1, HGNC:44359) is a long non-coding RNA gene on chromosome 17q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44359
Approved symbol	MAP3K14-AS1
Name	MAP3K14 antisense RNA 1
Location	17q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267278
Ensembl biotype	lncRNA
Entrez	100133991
RNAcentral	URS000075A4CB — lncRNA, 917 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 23 — 23 lncRNA

ENST00000585346, ENST00000585351, ENST00000585780, ENST00000586450, ENST00000588160, ENST00000588504, ENST00000588698, ENST00000590100, ENST00000591263, ENST00000592422, ENST00000655903, ENST00000657572, ENST00000663374, ENST00000782437, ENST00000782438, ENST00000782439, ENST00000782440, ENST00000782441, ENST00000782442, ENST00000782443, ENST00000782444, ENST00000782445, ENST00000782446

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000585346 — 3 exons

Exon	Start	End
ENSE00002841912	45255135	45255218
ENSE00002880390	45267113	45267466
ENSE00002894220	45247954	45248003

Expression profiles

Bgee: expression breadth ubiquitous, 160 present calls, max score 92.93.

FANTOM5 (CAGE): breadth broad, TPM avg 2.2301 / max 43.1173, expressed in 792 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
161291	1.0663	526
161290	0.9521	501
161289	0.1796	76
161292	0.0235	5
161293	0.0086	3

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	92.93	gold quality
left testis	UBERON:0004533	92.76	gold quality
testis	UBERON:0000473	88.65	gold quality
sperm	CL:0000019	82.09	silver quality
right uterine tube	UBERON:0001302	82.01	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.72	gold quality
small intestine Peyer’s patch	UBERON:0003454	78.81	gold quality
bone marrow cell	CL:0002092	78.43	gold quality
granulocyte	CL:0000094	78.40	gold quality
minor salivary gland	UBERON:0001830	77.33	gold quality
transverse colon	UBERON:0001157	76.85	gold quality
spleen	UBERON:0002106	75.81	gold quality
small intestine	UBERON:0002108	75.63	gold quality
body of stomach	UBERON:0001161	75.51	gold quality
rectum	UBERON:0001052	75.48	gold quality
mucosa of stomach	UBERON:0001199	75.31	gold quality
apex of heart	UBERON:0002098	75.30	gold quality
mucosa of transverse colon	UBERON:0004991	74.80	gold quality
saliva-secreting gland	UBERON:0001044	74.73	gold quality
body of pancreas	UBERON:0001150	74.61	gold quality
muscle layer of sigmoid colon	UBERON:0035805	74.38	gold quality
vermiform appendix	UBERON:0001154	74.05	gold quality
adenohypophysis	UBERON:0002196	73.88	gold quality
lymph node	UBERON:0000029	73.78	gold quality
left lobe of thyroid gland	UBERON:0001120	73.75	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.69	gold quality
right lobe of thyroid gland	UBERON:0001119	73.12	gold quality
upper lobe of left lung	UBERON:0008952	72.89	gold quality
metanephros cortex	UBERON:0010533	72.85	gold quality
left uterine tube	UBERON:0001303	72.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.67

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.