MAP3K4-AS1

Summary

MAP3K4-AS1 (MAP3K4 antisense RNA 1, HGNC:55048) is a long non-coding RNA gene on chromosome 6q26.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55048
Approved symbol	MAP3K4-AS1
Name	MAP3K4 antisense RNA 1
Location	6q26
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272841
Ensembl biotype	lncRNA
Entrez	117981787
RNAcentral	URS000008AA49 — lncRNA, 2025 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000608721

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000608721 — 1 exons

Exon	Start	End
ENSE00003710200	160990318	160992342

Expression profiles

Bgee: expression breadth ubiquitous, 196 present calls, max score 92.86.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.7856 / max 104.3754, expressed in 952 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
76557	2.1463	799
76558	0.4682	264
76556	0.1711	74

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
endothelial cell	CL:0000115	92.86	gold quality
decidua	UBERON:0002450	91.35	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.36	gold quality
Brodmann (1909) area 23	UBERON:0013554	80.29	gold quality
ventricular zone	UBERON:0003053	77.42	gold quality
cartilage tissue	UBERON:0002418	77.13	gold quality
esophagus squamous epithelium	UBERON:0006920	76.51	gold quality
entorhinal cortex	UBERON:0002728	76.13	gold quality
ganglionic eminence	UBERON:0004023	75.60	gold quality
smooth muscle tissue	UBERON:0001135	75.36	gold quality
Brodmann (1909) area 46	UBERON:0006483	73.80	gold quality
placenta	UBERON:0001987	73.76	gold quality
primary visual cortex	UBERON:0002436	73.62	gold quality
gall bladder	UBERON:0002110	73.52	gold quality
stromal cell of endometrium	CL:0002255	73.39	gold quality
palpebral conjunctiva	UBERON:0001812	72.94	gold quality
amniotic fluid	UBERON:0000173	72.66	gold quality
endocervix	UBERON:0000458	72.63	gold quality
cortical plate	UBERON:0005343	72.59	gold quality
anterior cingulate cortex	UBERON:0009835	72.59	gold quality
ectocervix	UBERON:0012249	72.55	gold quality
prefrontal cortex	UBERON:0000451	72.44	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	72.04	gold quality
temporal lobe	UBERON:0001871	71.82	gold quality
synovial joint	UBERON:0002217	71.43	gold quality
Brodmann (1909) area 9	UBERON:0013540	71.35	gold quality
epithelial cell of pancreas	CL:0000083	71.18	silver quality
myometrium	UBERON:0001296	71.13	gold quality
endometrium	UBERON:0001295	71.06	gold quality
islet of Langerhans	UBERON:0000006	70.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.