MAP3K5-AS1

Summary

MAP3K5-AS1 (MAP3K5 antisense RNA 1, HGNC:40358) is a long non-coding RNA gene on chromosome 6q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40358
Approved symbol	MAP3K5-AS1
Name	MAP3K5 antisense RNA 1
Location	6q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234263
Ensembl biotype	lncRNA
Entrez	101928461
RNAcentral	URS00007E47DC — lncRNA, 762 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000432477, ENST00000814997, ENST00000814998

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432477 — 3 exons

Exon	Start	End
ENSE00001684860	136636931	136637102
ENSE00001728173	136629066	136629276
ENSE00001749507	136647772	136648198

Expression profiles

Bgee: expression breadth ubiquitous, 150 present calls, max score 88.51.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0104 / max 9.3414, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
69972	0.0104	3

Top tissues by expression

248 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	88.51	gold quality
left testis	UBERON:0004533	86.17	gold quality
right testis	UBERON:0004534	85.26	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.49	gold quality
testis	UBERON:0000473	83.25	gold quality
adrenal tissue	UBERON:0018303	73.18	gold quality
cardiac muscle of right atrium	UBERON:0003379	69.93	gold quality
left ventricle myocardium	UBERON:0006566	69.70	gold quality
left adrenal gland cortex	UBERON:0035825	69.47	gold quality
right adrenal gland cortex	UBERON:0035827	69.33	gold quality
left adrenal gland	UBERON:0001234	68.85	gold quality
right adrenal gland	UBERON:0001233	68.57	gold quality
sural nerve	UBERON:0015488	67.83	silver quality
adrenal cortex	UBERON:0001235	67.64	gold quality
calcaneal tendon	UBERON:0003701	67.46	gold quality
adrenal gland	UBERON:0002369	67.33	gold quality
bone marrow cell	CL:0002092	66.62	silver quality
colonic epithelium	UBERON:0000397	65.17	silver quality
stromal cell of endometrium	CL:0002255	64.97	gold quality
adult organism	UBERON:0007023	64.45	gold quality
left ovary	UBERON:0002119	64.40	gold quality
ventricular zone	UBERON:0003053	62.33	gold quality
right ovary	UBERON:0002118	62.14	gold quality
ovary	UBERON:0000992	60.51	gold quality
right lung	UBERON:0002167	60.31	gold quality
monocyte	CL:0000576	59.91	gold quality
descending thoracic aorta	UBERON:0002345	59.73	gold quality
ascending aorta	UBERON:0001496	59.25	gold quality
thoracic aorta	UBERON:0001515	59.08	gold quality
myocardium	UBERON:0002349	58.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.