MAP3K5-AS2

Summary

MAP3K5-AS2 (MAP3K5 antisense RNA 2, HGNC:56125) is a long non-coding RNA gene on chromosome 6q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56125
Approved symbol	MAP3K5-AS2
Name	MAP3K5 antisense RNA 2
Location	6q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286646
Ensembl biotype	lncRNA
Entrez	101928429
RNAcentral	URS0000A76C07 — lncRNA, 868 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000661159

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000661159 — 2 exons

Exon	Start	End
ENSE00003986831	136785415	136786402
ENSE00004126216	136784007	136784274

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 90.99.

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	90.99	gold quality
leukocyte	CL:0000738	90.31	gold quality
bone marrow cell	CL:0002092	82.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.44	gold quality
bone marrow	UBERON:0002371	80.61	gold quality
granulocyte	CL:0000094	78.75	gold quality
blood	UBERON:0000178	77.11	gold quality
esophagus squamous epithelium	UBERON:0006920	76.79	gold quality
trabecular bone tissue	UBERON:0002483	74.85	gold quality
colonic epithelium	UBERON:0000397	71.59	gold quality
adrenal tissue	UBERON:0018303	71.56	gold quality
vermiform appendix	UBERON:0001154	71.43	gold quality
left adrenal gland cortex	UBERON:0035825	68.77	gold quality
right adrenal gland cortex	UBERON:0035827	67.58	gold quality
adrenal gland	UBERON:0002369	67.50	gold quality
left adrenal gland	UBERON:0001234	67.11	gold quality
amniotic fluid	UBERON:0000173	66.80	gold quality
lower lobe of lung	UBERON:0008949	66.56	gold quality
adrenal cortex	UBERON:0001235	66.55	gold quality
right adrenal gland	UBERON:0001233	66.24	gold quality
lymph node	UBERON:0000029	65.71	gold quality
spleen	UBERON:0002106	65.58	gold quality
smooth muscle tissue	UBERON:0001135	65.03	gold quality
caecum	UBERON:0001153	64.71	gold quality
lower esophagus mucosa	UBERON:0035834	64.63	gold quality
gall bladder	UBERON:0002110	63.88	gold quality
rectum	UBERON:0001052	63.41	gold quality
oral cavity	UBERON:0000167	62.47	gold quality
right lung	UBERON:0002167	61.98	gold quality
lung	UBERON:0002048	61.62	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.