MAP4K1-AS1

Summary

MAP4K1-AS1 (MAP4K1 antisense RNA 1, HGNC:55302) is a long non-coding RNA gene on chromosome 19q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55302
Approved symbol	MAP4K1-AS1
Name	MAP4K1 antisense RNA 1
Location	19q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267291
Ensembl biotype	lncRNA
Entrez	105372397
RNAcentral	URS0000A76C16 — lncRNA, 532 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000589557, ENST00000815714

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000589557 — 3 exons

Exon	Start	End
ENSE00002975503	38597253	38597395
ENSE00004217970	38596290	38596436
ENSE00004217972	38601413	38601705

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 92.89.

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	92.89	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.60	gold quality
gastrocnemius	UBERON:0001388	75.00	gold quality
muscle of leg	UBERON:0001383	74.34	gold quality
skeletal muscle tissue	UBERON:0001134	72.39	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.47	gold quality
granulocyte	CL:0000094	60.90	gold quality
lymph node	UBERON:0000029	60.47	gold quality
gall bladder	UBERON:0002110	60.00	gold quality
blood	UBERON:0000178	56.23	gold quality
bone marrow	UBERON:0002371	56.15	gold quality
leukocyte	CL:0000738	55.05	gold quality
monocyte	CL:0000576	54.17	gold quality
vermiform appendix	UBERON:0001154	53.72	gold quality
prefrontal cortex	UBERON:0000451	53.24	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.35	gold quality
spleen	UBERON:0002106	52.17	gold quality
lower esophagus mucosa	UBERON:0035834	52.17	gold quality
liver	UBERON:0002107	51.94	silver quality
hypothalamus	UBERON:0001898	51.60	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	50.18	gold quality
ectocervix	UBERON:0012249	49.82	gold quality
right lobe of liver	UBERON:0001114	49.66	silver quality
tonsil	UBERON:0002372	49.49	silver quality
right adrenal gland cortex	UBERON:0035827	49.33	gold quality
small intestine Peyer’s patch	UBERON:0003454	49.14	gold quality
multicellular organism	UBERON:0000468	48.69	gold quality
superior frontal gyrus	UBERON:0002661	47.70	silver quality
Brodmann (1909) area 9	UBERON:0013540	47.48	gold quality
right coronary artery	UBERON:0001625	47.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.38

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.