MAP4K3-DT

Summary

MAP4K3-DT (MAP4K3 divergent transcript, HGNC:54056) is a long non-coding RNA gene on chromosome 2p22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54056
Approved symbol	MAP4K3-DT
Name	MAP4K3 divergent transcript
Location	2p22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231312
Ensembl biotype	lncRNA
Entrez	728730
RNAcentral	URS00005B9820 — lncRNA, 2517 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000366187, ENST00000415640, ENST00000422128, ENST00000425775, ENST00000426083, ENST00000438649, ENST00000443038, ENST00000445520, ENST00000446698, ENST00000449569, ENST00000451547, ENST00000658048, ENST00000658057, ENST00000658319, ENST00000659562, ENST00000662313, ENST00000667600, ENST00000668952, ENST00000670934, ENST00000671403, ENST00000827213, ENST00000827214, ENST00000827215, ENST00000827216, ENST00000827217, ENST00000827218, ENST00000827219, ENST00000827220, ENST00000827221

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000366187 — 3 exons

Exon	Start	End
ENSE00002524077	39453839	39453931
ENSE00004238872	39437420	39437535
ENSE00004238880	39454297	39454895

Expression profiles

Bgee: expression breadth ubiquitous, 195 present calls, max score 92.41.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 8.4881 / max 200.9506, expressed in 1741 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
19851	8.3352	1739
19850	0.1529	45

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
oocyte	CL:0000023	92.41	gold quality
right hemisphere of cerebellum	UBERON:0014890	90.95	gold quality
cerebellar hemisphere	UBERON:0002245	90.68	gold quality
cerebellar cortex	UBERON:0002129	90.50	gold quality
right frontal lobe	UBERON:0002810	90.45	gold quality
cerebellum	UBERON:0002037	88.60	gold quality
secondary oocyte	CL:0000655	88.35	gold quality
sural nerve	UBERON:0015488	87.38	gold quality
Brodmann (1909) area 9	UBERON:0013540	87.01	gold quality
anterior cingulate cortex	UBERON:0009835	87.00	gold quality
primary visual cortex	UBERON:0002436	86.98	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	85.16	gold quality
prefrontal cortex	UBERON:0000451	84.66	gold quality
neocortex	UBERON:0001950	83.82	gold quality
metanephros cortex	UBERON:0010533	83.60	gold quality
right lobe of liver	UBERON:0001114	83.58	gold quality
frontal cortex	UBERON:0001870	83.55	gold quality
body of stomach	UBERON:0001161	83.06	gold quality
caudate nucleus	UBERON:0001873	82.87	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.56	gold quality
colonic epithelium	UBERON:0000397	82.37	gold quality
putamen	UBERON:0001874	82.20	gold quality
amygdala	UBERON:0001876	82.11	gold quality
left adrenal gland cortex	UBERON:0035825	82.08	gold quality
nucleus accumbens	UBERON:0001882	82.04	gold quality
right uterine tube	UBERON:0001302	81.99	gold quality
cerebral cortex	UBERON:0000956	81.90	gold quality
body of pancreas	UBERON:0001150	81.73	gold quality
bone marrow cell	CL:0002092	81.72	gold quality
hypothalamus	UBERON:0001898	81.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.36

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.