MAPK10-AS1

Summary

MAPK10-AS1 (MAPK10 antisense RNA 1, HGNC:40359) is a long non-coding RNA gene on chromosome 4q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40359
Approved symbol	MAPK10-AS1
Name	MAPK10 antisense RNA 1
Location	4q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250062
Ensembl biotype	lncRNA
Entrez	101929064
RNAcentral	URS000075C0BC — lncRNA, 978 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000509322, ENST00000511917, ENST00000757109, ENST00000757110

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000509322 — 3 exons

Exon	Start	End
ENSE00002037148	86127592	86127688
ENSE00002055238	86119984	86120601
ENSE00002079255	86117912	86117962

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 85.72.

Top tissues by expression

208 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	85.72	gold quality
left testis	UBERON:0004533	74.51	gold quality
testis	UBERON:0000473	71.63	gold quality
right testis	UBERON:0004534	71.47	gold quality
colonic epithelium	UBERON:0000397	68.50	silver quality
adrenal tissue	UBERON:0018303	67.39	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.84	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.88	gold quality
ganglionic eminence	UBERON:0004023	60.87	gold quality
corpus callosum	UBERON:0002336	55.60	gold quality
medial globus pallidus	UBERON:0002477	53.65	gold quality
right coronary artery	UBERON:0001625	52.73	gold quality
lower lobe of lung	UBERON:0008949	52.29	silver quality
stromal cell of endometrium	CL:0002255	52.27	silver quality
skin of hip	UBERON:0001554	51.84	silver quality
globus pallidus	UBERON:0001875	51.62	gold quality
monocyte	CL:0000576	51.60	silver quality
gall bladder	UBERON:0002110	50.71	gold quality
calcaneal tendon	UBERON:0003701	50.11	silver quality
islet of Langerhans	UBERON:0000006	50.03	gold quality
prefrontal cortex	UBERON:0000451	49.57	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.52	gold quality
muscle of leg	UBERON:0001383	49.08	gold quality
right atrium auricular region	UBERON:0006631	48.85	gold quality
vermiform appendix	UBERON:0001154	48.56	gold quality
cardiac atrium	UBERON:0002081	48.56	gold quality
buccal mucosa cell	CL:0002336	48.28	gold quality
endocervix	UBERON:0000458	47.63	gold quality
gastrocnemius	UBERON:0001388	47.41	gold quality
adrenal gland	UBERON:0002369	47.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.