MAPK6-DT

Summary

MAPK6-DT (MAPK6 divergent transcript, HGNC:53900) is a long non-coding RNA gene on chromosome 15q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53900
Approved symbol	MAPK6-DT
Name	MAPK6 divergent transcript
Location	15q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	lncMAPK6
Ensembl gene	ENSG00000259438
Ensembl biotype	lncRNA
Entrez	112543478
RNAcentral	URS0000364B61 — lncRNA, 865 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000561318

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561318 — 2 exons

Exon	Start	End
ENSE00002550065	52010999	52011466
ENSE00002555007	52018699	52019095

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 69.92.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	69.92	silver quality
skeletal muscle tissue	UBERON:0001134	63.89	gold quality
ventricular zone	UBERON:0003053	63.11	gold quality
bone marrow	UBERON:0002371	58.95	gold quality
stromal cell of endometrium	CL:0002255	58.54	gold quality
monocyte	CL:0000576	56.35	gold quality
calcaneal tendon	UBERON:0003701	56.09	gold quality
sural nerve	UBERON:0015488	53.72	silver quality
lymph node	UBERON:0000029	53.68	gold quality
prefrontal cortex	UBERON:0000451	52.81	gold quality
liver	UBERON:0002107	52.08	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.43	gold quality
right testis	UBERON:0004534	51.27	gold quality
left testis	UBERON:0004533	51.10	gold quality
blood	UBERON:0000178	51.01	gold quality
testis	UBERON:0000473	50.79	gold quality
duodenum	UBERON:0002114	50.43	gold quality
granulocyte	CL:0000094	50.32	silver quality
right lobe of liver	UBERON:0001114	50.28	gold quality
gall bladder	UBERON:0002110	50.27	gold quality
primary visual cortex	UBERON:0002436	50.26	gold quality
islet of Langerhans	UBERON:0000006	50.06	gold quality
muscle of leg	UBERON:0001383	49.20	gold quality
pancreas	UBERON:0001264	49.01	gold quality
gastrocnemius	UBERON:0001388	48.60	gold quality
endometrium	UBERON:0001295	48.47	gold quality
frontal cortex	UBERON:0001870	48.28	gold quality
placenta	UBERON:0001987	47.91	gold quality
right adrenal gland cortex	UBERON:0035827	47.72	gold quality
Ammon’s horn	UBERON:0001954	47.44	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.