MAPRE3-AS1

Summary

MAPRE3-AS1 (MAPRE3 antisense RNA 1, HGNC:40362) is a long non-coding RNA gene on chromosome 2p23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40362
Approved symbol	MAPRE3-AS1
Name	MAPRE3 antisense RNA 1
Location	2p23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000205500
Ensembl biotype	lncRNA
Entrez	100129724
RNAcentral	URS0000BC43F5 — lncRNA, 564 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 3 lncRNA, 1 retained_intron

ENST00000380387, ENST00000411685, ENST00000423923, ENST00000455081

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000380387 — 3 exons

Exon	Start	End
ENSE00001484754	27011769	27013464
ENSE00001558296	27013935	27014092
ENSE00001561519	27014501	27014612

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 83.82.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.82	gold quality
right testis	UBERON:0004534	76.30	gold quality
left testis	UBERON:0004533	75.91	gold quality
testis	UBERON:0000473	75.51	gold quality
sural nerve	UBERON:0015488	71.25	gold quality
bone marrow cell	CL:0002092	70.77	silver quality
colonic epithelium	UBERON:0000397	69.98	silver quality
skeletal muscle tissue	UBERON:0001134	63.86	silver quality
bone marrow	UBERON:0002371	63.23	gold quality
corpus callosum	UBERON:0002336	62.23	gold quality
tonsil	UBERON:0002372	61.61	silver quality
liver	UBERON:0002107	61.27	gold quality
calcaneal tendon	UBERON:0003701	60.88	gold quality
stromal cell of endometrium	CL:0002255	60.53	gold quality
monocyte	CL:0000576	60.37	gold quality
primary visual cortex	UBERON:0002436	59.44	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.43	gold quality
islet of Langerhans	UBERON:0000006	57.22	gold quality
cortex of kidney	UBERON:0001225	56.65	gold quality
left uterine tube	UBERON:0001303	56.63	gold quality
muscle of leg	UBERON:0001383	56.52	gold quality
gastrocnemius	UBERON:0001388	56.08	gold quality
blood	UBERON:0000178	55.65	gold quality
kidney	UBERON:0002113	55.03	gold quality
adrenal tissue	UBERON:0018303	54.82	gold quality
skin of leg	UBERON:0001511	54.04	gold quality
pancreas	UBERON:0001264	54.02	gold quality
prefrontal cortex	UBERON:0000451	53.82	gold quality
zone of skin	UBERON:0000014	53.68	gold quality
metanephros cortex	UBERON:0010533	53.61	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.67

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.