MARCHF11-AS1

Summary

MARCHF11-AS1 (MARCHF11 antisense RNA 1, HGNC:41287) is a long non-coding RNA gene on chromosome 5p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41287
Approved symbol	MARCHF11-AS1
Name	MARCHF11 antisense RNA 1
Location	5p15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250981
Ensembl biotype	lncRNA
Entrez	107986407
RNAcentral	URS0002A168E9 — lncRNA, 918 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000502834, ENST00000693453, ENST00000757738, ENST00000757739, ENST00000757740, ENST00000757741, ENST00000757742, ENST00000757743

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502834 — 2 exons

Exon	Start	End
ENSE00002025782	16141012	16141737
ENSE00004109153	16129103	16129294

Expression profiles

Bgee: expression breadth broad, 41 present calls, max score 72.80.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0213 / max 20.1253, expressed in 6 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55843	0.0090	2
55841	0.0060	4
55842	0.0047	3
203494	0.0016	1

Top tissues by expression

49 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
heart left ventricle	UBERON:0002084	72.80	gold quality
apex of heart	UBERON:0002098	71.88	gold quality
heart	UBERON:0000948	66.80	gold quality
quadriceps femoris	UBERON:0001377	63.33	gold quality
prostate gland	UBERON:0002367	59.58	gold quality
bone marrow	UBERON:0002371	59.57	silver quality
spleen	UBERON:0002106	58.67	silver quality
cerebellar vermis	UBERON:0004720	58.50	gold quality
multicellular organism	UBERON:0000468	57.52	gold quality
lung	UBERON:0002048	57.37	silver quality
thymus	UBERON:0002370	57.24	silver quality
endometrium	UBERON:0001295	57.14	gold quality
liver	UBERON:0002107	56.97	silver quality
skeletal muscle tissue	UBERON:0001134	55.70	silver quality
subcutaneous adipose tissue	UBERON:0002190	55.46	silver quality
blood	UBERON:0000178	53.33	gold quality
right atrium auricular region	UBERON:0006631	53.02	gold quality
kidney	UBERON:0002113	52.79	gold quality
monocyte	CL:0000576	51.87	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	49.90	silver quality
prefrontal cortex	UBERON:0000451	49.66	gold quality
hindlimb stylopod muscle	UBERON:0004252	48.59	gold quality
pancreas	UBERON:0001264	48.11	silver quality
body of pancreas	UBERON:0001150	46.00	gold quality
muscle of leg	UBERON:0001383	45.50	silver quality
primary visual cortex	UBERON:0002436	45.31	silver quality
gastrocnemius	UBERON:0001388	44.76	silver quality
frontal cortex	UBERON:0001870	44.30	silver quality
Brodmann (1909) area 9	UBERON:0013540	43.53	silver quality
skin of leg	UBERON:0001511	42.61	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.