MARCO-AS1

Summary

MARCO-AS1 (MARCO antisense RNA 1, HGNC:58466) is a long non-coding RNA gene on chromosome 2q14.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58466
Approved symbol	MARCO-AS1
Name	MARCO antisense RNA 1
Location	2q14.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259094
Ensembl biotype	lncRNA
Entrez	141858820

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000556770

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000556770 — 2 exons

Exon	Start	End
ENSE00002517228	118949306	118949922
ENSE00002533091	118952590	118952983

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 74.88.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	74.88	gold quality
granulocyte	CL:0000094	65.13	gold quality
skeletal muscle tissue	UBERON:0001134	59.83	silver quality
lung	UBERON:0002048	57.01	gold quality
lower esophagus mucosa	UBERON:0035834	56.61	gold quality
vermiform appendix	UBERON:0001154	55.84	gold quality
duodenum	UBERON:0002114	55.75	gold quality
tonsil	UBERON:0002372	55.70	gold quality
blood	UBERON:0000178	55.12	gold quality
upper lobe of left lung	UBERON:0008952	54.62	gold quality
stromal cell of endometrium	CL:0002255	53.68	silver quality
liver	UBERON:0002107	53.56	gold quality
monocyte	CL:0000576	53.39	gold quality
calcaneal tendon	UBERON:0003701	53.11	gold quality
right lung	UBERON:0002167	50.69	gold quality
bone marrow	UBERON:0002371	50.69	silver quality
prefrontal cortex	UBERON:0000451	50.52	silver quality
islet of Langerhans	UBERON:0000006	49.01	gold quality
lymph node	UBERON:0000029	48.95	gold quality
endometrium	UBERON:0001295	48.42	silver quality
left coronary artery	UBERON:0001626	48.28	gold quality
myometrium	UBERON:0001296	48.24	gold quality
mucosa of transverse colon	UBERON:0004991	48.09	gold quality
smooth muscle tissue	UBERON:0001135	47.90	gold quality
pancreas	UBERON:0001264	47.47	gold quality
muscle of leg	UBERON:0001383	47.43	silver quality
placenta	UBERON:0001987	47.19	gold quality
right adrenal gland cortex	UBERON:0035827	47.13	gold quality
descending thoracic aorta	UBERON:0002345	47.03	gold quality
urinary bladder	UBERON:0001255	46.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.