MAST4-AS1

Summary

MAST4-AS1 (MAST4 antisense RNA 1, HGNC:40865) is a long non-coding RNA gene on chromosome 5q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40865
Approved symbol	MAST4-AS1
Name	MAST4 antisense RNA 1
Location	5q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229666
Ensembl biotype	lncRNA
Entrez	101928794
RNAcentral	URS000075A0D8 — lncRNA, 743 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000451496, ENST00000766779, ENST00000766780

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000451496 — 2 exons

Exon	Start	End
ENSE00001594418	67001383	67002049
ENSE00004125816	67003844	67004250

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 82.09.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4694 / max 13.1549, expressed in 252 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
61968	0.4694	252

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.09	gold quality
monocyte	CL:0000576	75.12	gold quality
islet of Langerhans	UBERON:0000006	75.02	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	74.67	gold quality
leukocyte	CL:0000738	73.83	gold quality
esophagus mucosa	UBERON:0002469	71.18	gold quality
mucosa of transverse colon	UBERON:0004991	70.34	gold quality
right coronary artery	UBERON:0001625	70.04	gold quality
skeletal muscle tissue	UBERON:0001134	69.51	gold quality
thoracic aorta	UBERON:0001515	68.49	gold quality
ascending aorta	UBERON:0001496	68.47	gold quality
left coronary artery	UBERON:0001626	68.41	gold quality
esophagus	UBERON:0001043	67.50	gold quality
lower esophagus mucosa	UBERON:0035834	67.47	gold quality
descending thoracic aorta	UBERON:0002345	67.36	gold quality
saliva-secreting gland	UBERON:0001044	67.34	gold quality
muscle tissue	UBERON:0002385	67.32	gold quality
tonsil	UBERON:0002372	67.12	gold quality
minor salivary gland	UBERON:0001830	66.83	gold quality
placenta	UBERON:0001987	66.59	gold quality
popliteal artery	UBERON:0002250	66.53	gold quality
tibial artery	UBERON:0007610	66.53	gold quality
urinary bladder	UBERON:0001255	66.11	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.02	gold quality
pancreas	UBERON:0001264	65.87	gold quality
colonic epithelium	UBERON:0000397	65.80	silver quality
hindlimb stylopod muscle	UBERON:0004252	65.70	gold quality
muscle of leg	UBERON:0001383	64.98	gold quality
gastrocnemius	UBERON:0001388	64.80	gold quality
right atrium auricular region	UBERON:0006631	63.94	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.94

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.