MAST4-IT1

Summary

MAST4-IT1 (MAST4 intronic transcript 1, HGNC:41448) is a long non-coding RNA gene on chromosome 5q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41448
Approved symbol	MAST4-IT1
Name	MAST4 intronic transcript 1
Location	5q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249057
Ensembl biotype	lncRNA
Entrez	100874310
RNAcentral	URS0000349A5A — lncRNA, 658 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000514241

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000514241 — 1 exons

Exon	Start	End
ENSE00002071409	66662331	66662988

Expression profiles

Bgee: expression breadth broad, 76 present calls, max score 82.15.

Top tissues by expression

76 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.15	gold quality
skeletal muscle tissue	UBERON:0001134	68.54	silver quality
adrenal tissue	UBERON:0018303	66.21	gold quality
myometrium	UBERON:0001296	66.07	gold quality
tonsil	UBERON:0002372	65.62	gold quality
calcaneal tendon	UBERON:0003701	56.68	gold quality
endometrium	UBERON:0001295	54.75	gold quality
sural nerve	UBERON:0015488	54.56	silver quality
adrenal gland	UBERON:0002369	53.35	gold quality
kidney	UBERON:0002113	52.87	gold quality
adult mammalian kidney	UBERON:0000082	52.79	gold quality
monocyte	CL:0000576	51.84	gold quality
bone marrow	UBERON:0002371	51.30	silver quality
placenta	UBERON:0001987	51.25	silver quality
blood	UBERON:0000178	50.54	silver quality
muscle of leg	UBERON:0001383	50.48	silver quality
ovary	UBERON:0000992	49.27	silver quality
prefrontal cortex	UBERON:0000451	48.98	gold quality
gastrocnemius	UBERON:0001388	48.24	silver quality
pancreas	UBERON:0001264	47.69	gold quality
corpus callosum	UBERON:0002336	47.60	gold quality
heart	UBERON:0000948	47.07	gold quality
prostate gland	UBERON:0002367	46.95	silver quality
uterine cervix	UBERON:0000002	46.65	silver quality
intestine	UBERON:0000160	46.32	silver quality
primary visual cortex	UBERON:0002436	45.86	silver quality
multicellular organism	UBERON:0000468	45.27	gold quality
heart left ventricle	UBERON:0002084	45.23	gold quality
body of uterus	UBERON:0009853	45.18	gold quality
lung	UBERON:0002048	44.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.