MATN1-AS1

Summary

MATN1-AS1 (MATN1 antisense RNA 1, HGNC:40364) is a long non-coding RNA gene on chromosome 1p35.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40364
Approved symbol	MATN1-AS1
Name	MATN1 antisense RNA 1
Location	1p35.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000186056
Ensembl biotype	lncRNA
Entrez	100129196
RNAcentral	URS000075AA67 — lncRNA, 2065 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000414532, ENST00000414763, ENST00000443076, ENST00000454613, ENST00000649861, ENST00000702045, ENST00000830873

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414532 — 4 exons

Exon	Start	End
ENSE00001428684	30726243	30726744
ENSE00001430231	30725735	30726051
ENSE00001432307	30721288	30721722
ENSE00001629369	30718504	30721174

Expression profiles

Bgee: expression breadth ubiquitous, 187 present calls, max score 84.56.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.0729 / max 155.3265, expressed in 1363 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
1867	6.3629	1296
1866	0.7099	319

Top tissues by expression

234 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.56	gold quality
endocervix	UBERON:0000458	80.25	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	79.25	gold quality
left ovary	UBERON:0002119	78.38	gold quality
ectocervix	UBERON:0012249	77.19	gold quality
granulocyte	CL:0000094	77.18	gold quality
right uterine tube	UBERON:0001302	77.03	gold quality
body of uterus	UBERON:0009853	76.47	gold quality
spinal cord	UBERON:0002240	76.46	gold quality
right ovary	UBERON:0002118	76.08	gold quality
sural nerve	UBERON:0015488	75.66	gold quality
spleen	UBERON:0002106	75.23	gold quality
left uterine tube	UBERON:0001303	74.84	gold quality
uterine cervix	UBERON:0000002	74.37	gold quality
skin of leg	UBERON:0001511	73.82	gold quality
lymph node	UBERON:0000029	73.28	gold quality
skin of abdomen	UBERON:0001416	73.18	gold quality
gall bladder	UBERON:0002110	73.11	gold quality
ovary	UBERON:0000992	72.51	gold quality
lower esophagus mucosa	UBERON:0035834	72.35	gold quality
tibial nerve	UBERON:0001323	72.32	gold quality
small intestine Peyer’s patch	UBERON:0003454	71.90	gold quality
right lobe of thyroid gland	UBERON:0001119	71.52	gold quality
minor salivary gland	UBERON:0001830	71.24	gold quality
left lobe of thyroid gland	UBERON:0001120	71.17	gold quality
vermiform appendix	UBERON:0001154	71.13	gold quality
right lobe of liver	UBERON:0001114	70.65	gold quality
zone of skin	UBERON:0000014	70.56	gold quality
tibial artery	UBERON:0007610	70.56	gold quality
popliteal artery	UBERON:0002250	70.53	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.12

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LncRNA MATN1-AS1 for Prediction of Prognosis in Osteosarcoma Patients and Its Cellular Function. (PMID:34542816)
• Clinical significance of MATN1-AS1 as ceRNA of Mir-200b in tissues and serum of patients with cervical cancer. (PMID:37714866)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.