MAX-AS1

Summary

MAX-AS1 (MAX antisense RNA 1, HGNC:58293) is a long non-coding RNA gene on chromosome 14q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58293
Approved symbol	MAX-AS1
Name	MAX antisense RNA 1
Location	14q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259118
Ensembl biotype	lncRNA
Entrez	100506321
RNAcentral	URS000075C0ED — lncRNA, 895 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000553633, ENST00000555261, ENST00000555898, ENST00000556127, ENST00000719996

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553633 — 3 exons

Exon	Start	End
ENSE00002429919	65090535	65090647
ENSE00004038251	65089915	65090019
ENSE00004038253	65093632	65094212

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 86.39.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.39	gold quality
bone marrow	UBERON:0002371	84.43	gold quality
bone marrow cell	CL:0002092	81.91	gold quality
monocyte	CL:0000576	77.54	gold quality
leukocyte	CL:0000738	76.86	gold quality
colonic epithelium	UBERON:0000397	74.67	gold quality
blood	UBERON:0000178	73.21	gold quality
skeletal muscle tissue	UBERON:0001134	73.01	gold quality
testis	UBERON:0000473	71.62	gold quality
left testis	UBERON:0004533	71.13	gold quality
right testis	UBERON:0004534	70.46	gold quality
adrenal tissue	UBERON:0018303	68.01	gold quality
skin of abdomen	UBERON:0001416	67.79	gold quality
ventricular zone	UBERON:0003053	67.45	gold quality
zone of skin	UBERON:0000014	67.24	gold quality
vagina	UBERON:0000996	66.90	gold quality
granulocyte	CL:0000094	66.80	gold quality
skin of leg	UBERON:0001511	66.74	gold quality
tonsil	UBERON:0002372	66.69	gold quality
uterine cervix	UBERON:0000002	66.64	gold quality
sural nerve	UBERON:0015488	66.06	gold quality
urinary bladder	UBERON:0001255	65.80	gold quality
lung	UBERON:0002048	65.26	gold quality
ectocervix	UBERON:0012249	65.06	gold quality
upper lobe of left lung	UBERON:0008952	64.36	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.19	gold quality
esophagus mucosa	UBERON:0002469	63.93	gold quality
subcutaneous adipose tissue	UBERON:0002190	63.70	gold quality
left uterine tube	UBERON:0001303	63.69	gold quality
right lung	UBERON:0002167	62.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.53

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.