MBP-AS1

Summary

MBP-AS1 (MBP antisense RNA 1, HGNC:58315) is a long non-coding RNA gene on chromosome 18q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58315
Approved symbol	MBP-AS1
Name	MBP antisense RNA 1
Location	18q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000266844
Ensembl biotype	lncRNA
Entrez	105372217
RNAcentral	URS0002A39F5C — lncRNA, 859 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000577364, ENST00000580580, ENST00000582546, ENST00000582763, ENST00000583326, ENST00000583889, ENST00000834939

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000577364 — 2 exons

Exon	Start	End
ENSE00002696784	76978833	76979197
ENSE00002709945	76979356	76979553

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 99.66.

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	99.66	gold quality
tibial nerve	UBERON:0001323	96.81	gold quality
spinal cord	UBERON:0002240	94.35	gold quality
Brodmann (1909) area 9	UBERON:0013540	94.31	gold quality
right hemisphere of cerebellum	UBERON:0014890	91.72	gold quality
hypothalamus	UBERON:0001898	90.51	gold quality
colonic epithelium	UBERON:0000397	89.95	gold quality
putamen	UBERON:0001874	89.72	gold quality
amygdala	UBERON:0001876	89.66	gold quality
cerebellar cortex	UBERON:0002129	88.43	gold quality
cerebellar hemisphere	UBERON:0002245	88.26	gold quality
right frontal lobe	UBERON:0002810	85.99	gold quality
anterior cingulate cortex	UBERON:0009835	85.98	gold quality
sural nerve	UBERON:0015488	85.89	gold quality
cerebellum	UBERON:0002037	85.08	gold quality
substantia nigra	UBERON:0002038	84.34	gold quality
prefrontal cortex	UBERON:0000451	84.17	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	83.73	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.31	silver quality
nucleus accumbens	UBERON:0001882	82.36	gold quality
caudate nucleus	UBERON:0001873	80.65	gold quality
left testis	UBERON:0004533	80.26	gold quality
midbrain	UBERON:0001891	79.42	gold quality
neocortex	UBERON:0001950	78.45	gold quality
right testis	UBERON:0004534	78.22	gold quality
testis	UBERON:0000473	77.58	gold quality
Ammon’s horn	UBERON:0001954	77.54	gold quality
frontal cortex	UBERON:0001870	77.03	gold quality
brain	UBERON:0000955	76.81	gold quality
cerebral cortex	UBERON:0000956	76.44	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.