MCC-AS1

Summary

MCC-AS1 (MCC and TSSK1B antisense RNA 1, HGNC:40365) is a long non-coding RNA gene on chromosome 5q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40365
Approved symbol	MCC-AS1
Name	MCC and TSSK1B antisense RNA 1
Location	5q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232633
Ensembl biotype	lncRNA
Entrez	144834434

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000416046, ENST00000510381, ENST00000816718, ENST00000816719

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416046 — 5 exons

Exon	Start	End
ENSE00002046920	113428660	113428779
ENSE00002049586	113399943	113399999
ENSE00002076338	113323028	113323273
ENSE00004219747	113435545	113436342
ENSE00004219749	113433027	113435167

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 72.17.

Top tissues by expression

102 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.17	gold quality
right testis	UBERON:0004534	65.03	gold quality
left testis	UBERON:0004533	64.50	gold quality
testis	UBERON:0000473	64.00	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.86	silver quality
cortical plate	UBERON:0005343	60.38	silver quality
skeletal muscle tissue	UBERON:0001134	58.96	silver quality
ventricular zone	UBERON:0003053	57.85	silver quality
ganglionic eminence	UBERON:0004023	56.93	silver quality
calcaneal tendon	UBERON:0003701	55.99	silver quality
sural nerve	UBERON:0015488	54.18	silver quality
placenta	UBERON:0001987	53.11	gold quality
right ovary	UBERON:0002118	52.73	gold quality
prefrontal cortex	UBERON:0000451	52.63	gold quality
cortex of kidney	UBERON:0001225	51.32	silver quality
ovary	UBERON:0000992	51.16	gold quality
lymph node	UBERON:0000029	50.63	silver quality
left ovary	UBERON:0002119	50.52	gold quality
liver	UBERON:0002107	49.95	silver quality
right lobe of liver	UBERON:0001114	49.91	silver quality
islet of Langerhans	UBERON:0000006	49.55	gold quality
blood	UBERON:0000178	49.03	gold quality
frontal cortex	UBERON:0001870	47.96	gold quality
superior frontal gyrus	UBERON:0002661	47.81	silver quality
primary visual cortex	UBERON:0002436	47.69	silver quality
endometrium	UBERON:0001295	47.03	gold quality
muscle of leg	UBERON:0001383	46.81	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	46.08	silver quality
multicellular organism	UBERON:0000468	45.78	gold quality
kidney	UBERON:0002113	45.70	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.