MCFD2-AS1
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Summary
MCFD2-AS1 (MCFD2 antisense RNA 1, HGNC:58223) is a long non-coding RNA gene on chromosome 2p21.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:58223 |
| Approved symbol | MCFD2-AS1 |
| Name | MCFD2 antisense RNA 1 |
| Location | 2p21 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000228925 |
| Ensembl biotype | lncRNA |
| Entrez | 139355231 |
| RNAcentral | URS0002A2A7B5 — lncRNA, 1874 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 lncRNA
ENST00000429761
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000429761 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00004113425 | 46899236 | 46899314 |
| ENSE00004113426 | 46906884 | 46908678 |
Expression profiles
Bgee: expression breadth ubiquitous, 133 present calls, max score 79.15.
Top tissues by expression
133 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 79.15 | silver quality |
| body of pancreas | UBERON:0001150 | 71.23 | gold quality |
| left adrenal gland cortex | UBERON:0035825 | 68.39 | gold quality |
| left adrenal gland | UBERON:0001234 | 68.04 | gold quality |
| bone marrow cell | CL:0002092 | 67.38 | silver quality |
| adrenal gland | UBERON:0002369 | 67.03 | gold quality |
| stromal cell of endometrium | CL:0002255 | 66.66 | gold quality |
| right adrenal gland | UBERON:0001233 | 66.57 | gold quality |
| right adrenal gland cortex | UBERON:0035827 | 66.20 | gold quality |
| tonsil | UBERON:0002372 | 65.95 | gold quality |
| pancreas | UBERON:0001264 | 65.60 | gold quality |
| mucosa of stomach | UBERON:0001199 | 65.49 | gold quality |
| left ovary | UBERON:0002119 | 64.91 | gold quality |
| ovary | UBERON:0000992 | 64.62 | gold quality |
| colonic epithelium | UBERON:0000397 | 64.15 | silver quality |
| left lobe of thyroid gland | UBERON:0001120 | 63.97 | gold quality |
| saliva-secreting gland | UBERON:0001044 | 63.96 | gold quality |
| minor salivary gland | UBERON:0001830 | 63.58 | gold quality |
| thyroid gland | UBERON:0002046 | 63.48 | gold quality |
| right ovary | UBERON:0002118 | 63.42 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 62.92 | gold quality |
| descending thoracic aorta | UBERON:0002345 | 62.81 | gold quality |
| bone marrow | UBERON:0002371 | 62.77 | gold quality |
| adrenal tissue | UBERON:0018303 | 62.42 | gold quality |
| right lobe of thyroid gland | UBERON:0001119 | 62.32 | gold quality |
| ascending aorta | UBERON:0001496 | 62.31 | gold quality |
| thoracic aorta | UBERON:0001515 | 62.28 | gold quality |
| popliteal artery | UBERON:0002250 | 61.81 | gold quality |
| tibial artery | UBERON:0007610 | 61.78 | gold quality |
| muscle tissue | UBERON:0002385 | 61.64 | gold quality |
Single-cell (SCXA)
Detected in 2 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-MTAB-9543 | yes | 7.89 |
| E-ANND-3 | no | 2.71 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): factor 5 and Factor VIII, combined deficiency of, 2