MCM8-AS1

Summary

MCM8-AS1 (MCM8 antisense RNA 1, HGNC:51230) is a long non-coding RNA gene on chromosome 20p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51230
Approved symbol	MCM8-AS1
Name	MCM8 antisense RNA 1
Location	20p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000278719
Ensembl biotype	lncRNA
Entrez	101929225
RNAcentral	URS000075A9A5 — lncRNA, 1138 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000613522, ENST00000723982, ENST00000723983, ENST00000723984

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000613522 — 5 exons

Exon	Start	End
ENSE00003721527	5993794	5993924
ENSE00003723324	6001276	6001397
ENSE00003730430	6005773	6005821
ENSE00003751575	6000521	6000675
ENSE00003752660	5990943	5991468

Expression profiles

Bgee: expression breadth ubiquitous, 148 present calls, max score 91.49.

Top tissues by expression

236 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	91.49	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.84	gold quality
sural nerve	UBERON:0015488	75.19	gold quality
right testis	UBERON:0004534	73.42	gold quality
left testis	UBERON:0004533	72.06	gold quality
testis	UBERON:0000473	69.74	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.04	gold quality
ganglionic eminence	UBERON:0004023	62.65	gold quality
granulocyte	CL:0000094	60.55	gold quality
buccal mucosa cell	CL:0002336	58.57	gold quality
apex of heart	UBERON:0002098	56.95	gold quality
monocyte	CL:0000576	56.29	gold quality
lower esophagus mucosa	UBERON:0035834	56.08	gold quality
calcaneal tendon	UBERON:0003701	56.01	silver quality
blood	UBERON:0000178	53.74	gold quality
cerebellar hemisphere	UBERON:0002245	53.35	gold quality
cerebellar cortex	UBERON:0002129	53.32	gold quality
ectocervix	UBERON:0012249	53.19	gold quality
adrenal tissue	UBERON:0018303	53.17	gold quality
right adrenal gland cortex	UBERON:0035827	53.08	gold quality
right hemisphere of cerebellum	UBERON:0014890	53.01	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.92	gold quality
muscle of leg	UBERON:0001383	52.85	gold quality
mucosa of stomach	UBERON:0001199	52.71	gold quality
vermiform appendix	UBERON:0001154	52.57	gold quality
lymph node	UBERON:0000029	52.40	gold quality
gastrocnemius	UBERON:0001388	52.37	gold quality
cerebellum	UBERON:0002037	52.34	gold quality
smooth muscle tissue	UBERON:0001135	51.88	gold quality
stromal cell of endometrium	CL:0002255	51.49	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.