ME3-AS1

Summary

ME3-AS1 (Me3 antisense RNA 1, HGNC:58438) is a long non-coding RNA gene on chromosome 11q14.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58438
Approved symbol	ME3-AS1
Name	Me3 antisense RNA 1
Location	11q14.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254733
Ensembl biotype	lncRNA
Entrez	141731998

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000524610, ENST00000758792

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000524610 — 3 exons

Exon	Start	End
ENSE00002176828	86432419	86432642
ENSE00004111012	86431475	86431633
ENSE00004111015	86622725	86623483

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 85.07.

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.07	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.25	gold quality
sural nerve	UBERON:0015488	75.51	gold quality
lymph node	UBERON:0000029	64.06	gold quality
gall bladder	UBERON:0002110	62.18	gold quality
smooth muscle tissue	UBERON:0001135	62.17	gold quality
bone marrow	UBERON:0002371	61.29	gold quality
skeletal muscle tissue	UBERON:0001134	59.03	silver quality
monocyte	CL:0000576	58.21	gold quality
placenta	UBERON:0001987	57.95	gold quality
islet of Langerhans	UBERON:0000006	57.53	gold quality
corpus callosum	UBERON:0002336	57.49	gold quality
vermiform appendix	UBERON:0001154	56.95	gold quality
left testis	UBERON:0004533	56.82	gold quality
testis	UBERON:0000473	56.64	gold quality
calcaneal tendon	UBERON:0003701	56.26	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.19	gold quality
right testis	UBERON:0004534	55.45	gold quality
cortex of kidney	UBERON:0001225	55.27	gold quality
blood	UBERON:0000178	54.79	gold quality
prefrontal cortex	UBERON:0000451	53.45	gold quality
kidney	UBERON:0002113	51.86	gold quality
muscle of leg	UBERON:0001383	51.68	gold quality
gastrocnemius	UBERON:0001388	50.56	gold quality
granulocyte	CL:0000094	50.18	silver quality
heart left ventricle	UBERON:0002084	49.39	gold quality
liver	UBERON:0002107	49.37	silver quality
body of pancreas	UBERON:0001150	48.50	gold quality
stomach	UBERON:0000945	48.25	gold quality
multicellular organism	UBERON:0000468	47.53	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.