MED14OS

Summary

MED14OS (MED14 opposite strand, HGNC:40162) is a long non-coding RNA gene on chromosome Xp11.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40162
Approved symbol	MED14OS
Name	MED14 opposite strand
Location	Xp11.4
Locus type	gene with protein product
Status	Approved
Ensembl gene	ENSG00000234636
Ensembl biotype	lncRNA
Entrez	100873985

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000456333

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456333 — 2 exons

Exon	Start	End
ENSE00004036120	40738193	40738897
ENSE00004036121	40735385	40735790

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 89.58.

FANTOM5 (CAGE): breadth broad, TPM avg 1.3666 / max 39.2350, expressed in 542 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
196001	1.3666	542

Top tissues by expression

243 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.58	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.33	gold quality
buccal mucosa cell	CL:0002336	80.94	silver quality
parotid gland	UBERON:0001831	75.85	gold quality
monocyte	CL:0000576	72.37	gold quality
leukocyte	CL:0000738	72.23	gold quality
muscle of leg	UBERON:0001383	71.80	gold quality
gastrocnemius	UBERON:0001388	71.41	gold quality
hindlimb stylopod muscle	UBERON:0004252	71.20	gold quality
bone marrow cell	CL:0002092	68.79	silver quality
ventricular zone	UBERON:0003053	68.39	gold quality
granulocyte	CL:0000094	67.38	gold quality
popliteal artery	UBERON:0002250	65.63	gold quality
tibial artery	UBERON:0007610	65.63	gold quality
ganglionic eminence	UBERON:0004023	65.45	gold quality
right coronary artery	UBERON:0001625	64.23	gold quality
left coronary artery	UBERON:0001626	64.02	gold quality
smooth muscle tissue	UBERON:0001135	63.28	gold quality
aorta	UBERON:0000947	62.92	gold quality
coronary artery	UBERON:0001621	62.75	gold quality
prefrontal cortex	UBERON:0000451	62.56	gold quality
cortical plate	UBERON:0005343	62.07	gold quality
omental fat pad	UBERON:0010414	61.98	gold quality
lower esophagus muscularis layer	UBERON:0035833	61.93	gold quality
peritoneum	UBERON:0002358	61.92	gold quality
lower esophagus	UBERON:0013473	61.90	gold quality
left lobe of thyroid gland	UBERON:0001120	61.49	gold quality
muscle tissue	UBERON:0002385	61.39	gold quality
adipose tissue of abdominal region	UBERON:0007808	61.16	gold quality
anterior cingulate cortex	UBERON:0009835	61.00	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.78

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

48 targeting MED14OS, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-3646	100.00	73.56	5283
HSA-MIR-3134	100.00	66.43	777
HSA-MIR-4531	99.99	69.70	3181
HSA-MIR-3662	99.99	73.82	5684
HSA-MIR-4534	99.99	66.58	1907
HSA-MIR-5696	99.98	72.36	4487
HSA-MIR-3148	99.97	75.06	6478
HSA-MIR-3688-3P	99.97	72.02	2834
HSA-MIR-9-3P	99.96	70.88	2068
HSA-MIR-570-3P	99.96	72.41	4910
HSA-MIR-23A-3P	99.95	74.24	3163
HSA-MIR-23B-3P	99.95	74.24	3163
HSA-MIR-23C	99.95	73.92	3192
HSA-MIR-8082	99.95	67.27	1170
HSA-MIR-101-3P	99.94	75.03	2230
HSA-MIR-335-3P	99.93	73.36	4958
HSA-MIR-552-5P	99.93	68.56	1583
HSA-MIR-497-5P	99.92	71.83	2674
HSA-MIR-16-5P	99.90	72.80	2780
HSA-MIR-195-5P	99.90	72.81	2805
HSA-MIR-15A-5P	99.90	72.80	2787
HSA-MIR-15B-5P	99.90	72.78	2798
HSA-MIR-424-5P	99.89	71.90	2641
HSA-MIR-6838-5P	99.89	71.94	2690
HSA-MIR-10395-5P	99.86	67.35	676
HSA-MIR-320A-3P	99.77	69.73	2107
HSA-MIR-320B	99.77	69.73	2107
HSA-MIR-320C	99.77	69.73	2107
HSA-MIR-320D	99.77	69.73	2107
HSA-MIR-4429	99.77	69.62	2111

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.