MED28-DT

Summary

MED28-DT (MED28 divergent transcript, HGNC:55567) is a long non-coding RNA gene on chromosome 4p15.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55567
Approved symbol	MED28-DT
Name	MED28 divergent transcript
Location	4p15.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	LAP3-AS1, AC006160.1
Ensembl gene	ENSG00000249502
Ensembl biotype	lncRNA
Entrez	121232375
RNAcentral	URS00026A1D01 — lncRNA, 2148 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000511010, ENST00000652378

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000511010 — 3 exons

Exon	Start	End
ENSE00002045775	17586336	17587679
ENSE00002069350	17613932	17614038
ENSE00003849655	17614142	17614585

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 75.71.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.71	silver quality
bone marrow cell	CL:0002092	70.04	gold quality
colonic epithelium	UBERON:0000397	65.42	silver quality
sural nerve	UBERON:0015488	64.14	silver quality
lymph node	UBERON:0000029	62.41	gold quality
vermiform appendix	UBERON:0001154	62.09	gold quality
bone marrow	UBERON:0002371	61.97	gold quality
apex of heart	UBERON:0002098	60.97	gold quality
liver	UBERON:0002107	60.89	gold quality
ganglionic eminence	UBERON:0004023	60.73	gold quality
monocyte	CL:0000576	59.99	gold quality
tonsil	UBERON:0002372	59.76	gold quality
leukocyte	CL:0000738	59.67	gold quality
right lobe of liver	UBERON:0001114	59.66	gold quality
cortical plate	UBERON:0005343	59.50	gold quality
skeletal muscle tissue	UBERON:0001134	59.44	gold quality
ventricular zone	UBERON:0003053	58.28	silver quality
stromal cell of endometrium	CL:0002255	58.12	gold quality
subcutaneous adipose tissue	UBERON:0002190	57.54	gold quality
right coronary artery	UBERON:0001625	57.51	gold quality
corpus callosum	UBERON:0002336	57.04	gold quality
calcaneal tendon	UBERON:0003701	56.83	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.41	gold quality
muscle of leg	UBERON:0001383	56.07	gold quality
gastrocnemius	UBERON:0001388	55.99	gold quality
adipose tissue	UBERON:0001013	55.94	gold quality
placenta	UBERON:0001987	55.72	gold quality
endometrium	UBERON:0001295	55.52	gold quality
tibial nerve	UBERON:0001323	55.43	gold quality
right adrenal gland cortex	UBERON:0035827	55.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.