MED8-AS1

Summary

MED8-AS1 (MED8 antisense RNA 1, HGNC:40908) is a long non-coding RNA gene on chromosome 1p34.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40908
Approved symbol	MED8-AS1
Name	MED8 antisense RNA 1
Location	1p34.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229431
Ensembl biotype	lncRNA
Entrez	107984947
RNAcentral	URS0002A26961 — lncRNA, 1383 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000436713, ENST00000686069, ENST00000752766, ENST00000752767, ENST00000752855, ENST00000752856, ENST00000752857

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436713 — 4 exons

Exon	Start	End
ENSE00001618104	43385113	43385141
ENSE00001681113	43387509	43387664
ENSE00001690872	43388706	43389155
ENSE00001797225	43385284	43385379

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 79.44.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pituitary gland	UBERON:0000007	79.44	gold quality
adenohypophysis	UBERON:0002196	78.41	gold quality
sural nerve	UBERON:0015488	77.81	gold quality
colonic epithelium	UBERON:0000397	77.05	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	73.15	gold quality
right lobe of liver	UBERON:0001114	72.33	gold quality
right frontal lobe	UBERON:0002810	72.22	gold quality
substantia nigra	UBERON:0002038	71.96	gold quality
left lobe of thyroid gland	UBERON:0001120	71.74	gold quality
subcutaneous adipose tissue	UBERON:0002190	71.69	gold quality
body of pancreas	UBERON:0001150	71.66	gold quality
granulocyte	CL:0000094	71.45	gold quality
esophagus mucosa	UBERON:0002469	71.40	gold quality
bone marrow	UBERON:0002371	71.30	gold quality
superior frontal gyrus	UBERON:0002661	71.23	gold quality
left testis	UBERON:0004533	71.18	gold quality
endometrium	UBERON:0001295	71.09	gold quality
thyroid gland	UBERON:0002046	70.95	gold quality
right testis	UBERON:0004534	70.88	gold quality
stromal cell of endometrium	CL:0002255	70.86	gold quality
lower esophagus mucosa	UBERON:0035834	70.78	gold quality
right adrenal gland cortex	UBERON:0035827	70.76	gold quality
testis	UBERON:0000473	70.65	gold quality
adipose tissue	UBERON:0001013	70.58	gold quality
hypothalamus	UBERON:0001898	70.55	gold quality
apex of heart	UBERON:0002098	70.32	gold quality
right lobe of thyroid gland	UBERON:0001119	70.30	gold quality
right adrenal gland	UBERON:0001233	70.19	gold quality
left adrenal gland cortex	UBERON:0035825	70.15	gold quality
right hemisphere of cerebellum	UBERON:0014890	70.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.