MEF2C-AS2

Summary

MEF2C-AS2 (MEF2C antisense RNA 2, HGNC:53115) is a long non-coding RNA gene on chromosome 5q14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53115
Approved symbol	MEF2C-AS2
Name	MEF2C antisense RNA 2
Location	5q14.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	CTC-467M3.1
Ensembl gene	ENSG00000245864
Ensembl biotype	lncRNA
Entrez	109729137
RNAcentral	URS0000102BD3 — ncRNA, 463 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000510274, ENST00000657578, ENST00000659116, ENST00000661038, ENST00000686200, ENST00000691963, ENST00000702330, ENST00000718055, ENST00000718056, ENST00000787848, ENST00000787849, ENST00000787850, ENST00000787851, ENST00000787852, ENST00000787853, ENST00000787854

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000510274 — 4 exons

Exon	Start	End
ENSE00001961560	88705523	88705656
ENSE00002053338	88712791	88712865
ENSE00002069522	88676218	88676263
ENSE00002085501	88722624	88722831

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 80.63.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2805 / max 32.0460, expressed in 113 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
57491	0.1574	70
57492	0.1231	60

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.63	gold quality
ventricular zone	UBERON:0003053	79.23	gold quality
ganglionic eminence	UBERON:0004023	77.73	gold quality
bone marrow cell	CL:0002092	74.79	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.52	gold quality
cerebellar hemisphere	UBERON:0002245	72.70	gold quality
cerebellum	UBERON:0002037	72.61	gold quality
cerebellar cortex	UBERON:0002129	72.60	gold quality
cortical plate	UBERON:0005343	72.35	gold quality
right hemisphere of cerebellum	UBERON:0014890	72.21	gold quality
adrenal tissue	UBERON:0018303	72.03	gold quality
skeletal muscle tissue	UBERON:0001134	71.56	gold quality
corpus callosum	UBERON:0002336	71.37	gold quality
calcaneal tendon	UBERON:0003701	71.32	gold quality
colonic epithelium	UBERON:0000397	69.69	silver quality
hindlimb stylopod muscle	UBERON:0004252	69.15	gold quality
muscle of leg	UBERON:0001383	67.95	gold quality
gastrocnemius	UBERON:0001388	67.00	gold quality
nucleus accumbens	UBERON:0001882	66.06	gold quality
bone marrow	UBERON:0002371	65.79	gold quality
anterior cingulate cortex	UBERON:0009835	65.07	gold quality
primary visual cortex	UBERON:0002436	64.48	gold quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
superior frontal gyrus	UBERON:0002661	63.84	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	63.81	gold quality
Brodmann (1909) area 9	UBERON:0013540	63.71	gold quality
brain	UBERON:0000955	63.68	gold quality
prefrontal cortex	UBERON:0000451	63.67	gold quality
cerebral cortex	UBERON:0000956	63.58	gold quality
right frontal lobe	UBERON:0002810	63.51	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.