MEGF10-DT

Summary

MEGF10-DT (MEGF10 divergent transcript, HGNC:59126) is a long non-coding RNA gene on chromosome 5q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:59126
Approved symbol	MEGF10-DT
Name	MEGF10 divergent transcript
Location	5q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286615
Ensembl biotype	lncRNA
Entrez	105379199

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000652915, ENST00000653631, ENST00000654401, ENST00000656856, ENST00000659841, ENST00000660668, ENST00000670868, ENST00000701001, ENST00000753048, ENST00000753049, ENST00000753050, ENST00000753051, ENST00000753052, ENST00000753053, ENST00000753054, ENST00000753055

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000652915 — 4 exons

Exon	Start	End
ENSE00003858662	127233193	127233529
ENSE00003861786	127290614	127290731
ENSE00003876674	127282213	127282309
ENSE00003881476	127264502	127264718

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 80.39.

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.39	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	73.20	gold quality
ventricular zone	UBERON:0003053	71.08	gold quality
putamen	UBERON:0001874	69.76	gold quality
corpus callosum	UBERON:0002336	69.71	gold quality
caudate nucleus	UBERON:0001873	68.97	gold quality
substantia nigra	UBERON:0002038	68.80	gold quality
nucleus accumbens	UBERON:0001882	68.22	gold quality
skeletal muscle tissue	UBERON:0001134	67.98	gold quality
temporal lobe	UBERON:0001871	67.88	gold quality
amygdala	UBERON:0001876	67.85	gold quality
Ammon’s horn	UBERON:0001954	66.09	gold quality
ganglionic eminence	UBERON:0004023	64.72	gold quality
hypothalamus	UBERON:0001898	63.82	gold quality
Brodmann (1909) area 9	UBERON:0013540	63.79	gold quality
cerebral cortex	UBERON:0000956	63.70	gold quality
anterior cingulate cortex	UBERON:0009835	63.55	gold quality
prefrontal cortex	UBERON:0000451	63.45	gold quality
frontal cortex	UBERON:0001870	63.28	gold quality
primary visual cortex	UBERON:0002436	63.18	gold quality
right frontal lobe	UBERON:0002810	63.13	gold quality
brain	UBERON:0000955	63.11	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	63.05	gold quality
superior frontal gyrus	UBERON:0002661	61.35	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.25	gold quality
tonsil	UBERON:0002372	59.32	gold quality
calcaneal tendon	UBERON:0003701	58.99	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.52	gold quality
muscle of leg	UBERON:0001383	58.28	gold quality
cortical plate	UBERON:0005343	57.97	silver quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.