MEIS1-AS2

Summary

MEIS1-AS2 (MEIS1 antisense RNA 2, HGNC:40370) is a long non-coding RNA gene on chromosome 2p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40370
Approved symbol	MEIS1-AS2
Name	MEIS1 antisense RNA 2
Location	2p14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230749
Ensembl biotype	lncRNA
Entrez	100873998
RNAcentral	URS000081216E — lncRNA, 709 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000439433, ENST00000454595, ENST00000666153, ENST00000818475

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439433 — 2 exons

Exon	Start	End
ENSE00004201234	66439088	66439689
ENSE00004201235	66440225	66440405

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 83.16.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0594 / max 5.8120, expressed in 18 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
28822	0.0594	18

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.16	gold quality
adrenal tissue	UBERON:0018303	78.37	gold quality
sural nerve	UBERON:0015488	74.99	gold quality
colonic epithelium	UBERON:0000397	74.98	gold quality
left adrenal gland cortex	UBERON:0035825	72.63	gold quality
adrenal gland	UBERON:0002369	72.15	gold quality
stromal cell of endometrium	CL:0002255	71.77	gold quality
left adrenal gland	UBERON:0001234	71.72	gold quality
right adrenal gland	UBERON:0001233	71.52	gold quality
tonsil	UBERON:0002372	71.26	gold quality
uterine cervix	UBERON:0000002	70.29	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.21	gold quality
mucosa of stomach	UBERON:0001199	69.20	gold quality
right adrenal gland cortex	UBERON:0035827	69.09	gold quality
body of uterus	UBERON:0009853	68.94	gold quality
myometrium	UBERON:0001296	68.62	gold quality
right lung	UBERON:0002167	66.54	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	66.45	gold quality
monocyte	CL:0000576	66.42	gold quality
endocervix	UBERON:0000458	65.77	gold quality
ectocervix	UBERON:0012249	65.65	gold quality
body of pancreas	UBERON:0001150	65.63	gold quality
left uterine tube	UBERON:0001303	65.61	gold quality
endometrium	UBERON:0001295	65.57	gold quality
leukocyte	CL:0000738	65.54	gold quality
urinary bladder	UBERON:0001255	65.37	gold quality
lung	UBERON:0002048	65.15	gold quality
pancreas	UBERON:0001264	64.94	gold quality
lower esophagus muscularis layer	UBERON:0035833	64.42	gold quality
lower esophagus	UBERON:0013473	64.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.