MEIS1-AS3

Summary

MEIS1-AS3 (MEIS1 antisense RNA 3, HGNC:40369) is a long non-coding RNA gene on chromosome 2p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40369
Approved symbol	MEIS1-AS3
Name	MEIS1 antisense RNA 3
Location	2p14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226819
Ensembl biotype	lncRNA
Entrez	730198
RNAcentral	URS000075A690 — lncRNA, 4115 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000454167, ENST00000812466, ENST00000812467, ENST00000812468, ENST00000812469

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000454167 — 4 exons

Exon	Start	End
ENSE00001622795	66431931	66432010
ENSE00001638269	66433291	66433470
ENSE00001805427	66426735	66427162
ENSE00002444371	66431820	66431838

Expression profiles

Bgee: expression breadth ubiquitous, 107 present calls, max score 62.58.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2353 / max 11.9566, expressed in 136 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
28819	0.2353	136

Top tissues by expression

107 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	62.58	gold quality
fallopian tube	UBERON:0003889	61.09	gold quality
ectocervix	UBERON:0012249	58.86	gold quality
gall bladder	UBERON:0002110	58.75	gold quality
mucosa of stomach	UBERON:0001199	57.99	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	57.36	gold quality
fundus of stomach	UBERON:0001160	55.76	gold quality
left uterine tube	UBERON:0001303	55.38	gold quality
lower esophagus muscularis layer	UBERON:0035833	55.34	gold quality
lower esophagus	UBERON:0013473	55.19	gold quality
endometrium	UBERON:0001295	55.12	gold quality
urinary bladder	UBERON:0001255	54.39	gold quality
stomach	UBERON:0000945	54.09	gold quality
endocervix	UBERON:0000458	53.22	gold quality
cortex of kidney	UBERON:0001225	52.58	gold quality
body of stomach	UBERON:0001161	52.52	gold quality
monocyte	CL:0000576	52.10	silver quality
muscle layer of sigmoid colon	UBERON:0035805	51.75	gold quality
esophagus	UBERON:0001043	51.49	gold quality
prefrontal cortex	UBERON:0000451	51.31	gold quality
kidney	UBERON:0002113	51.29	gold quality
islet of Langerhans	UBERON:0000006	51.11	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.91	gold quality
colon	UBERON:0001155	50.51	gold quality
metanephros cortex	UBERON:0010533	50.45	gold quality
intestine	UBERON:0000160	50.44	gold quality
prostate gland	UBERON:0002367	50.35	gold quality
smooth muscle tissue	UBERON:0001135	50.30	gold quality
body of uterus	UBERON:0009853	49.79	gold quality
small intestine	UBERON:0002108	49.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.