MFAP3L-AS1

Summary

MFAP3L-AS1 (MFAP3L antisense RNA 1, HGNC:58419) is a long non-coding RNA gene on chromosome 4q33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58419
Approved symbol	MFAP3L-AS1
Name	MFAP3L antisense RNA 1
Location	4q33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249955
Ensembl biotype	lncRNA
Entrez	141731992

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000508955

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508955 — 3 exons

Exon	Start	End
ENSE00002045836	169990317	169990469
ENSE00004041983	169993548	169994510
ENSE00004041984	169981609	169981888

Expression profiles

Bgee: expression breadth broad, 99 present calls, max score 79.40.

Top tissues by expression

197 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.40	silver quality
endometrium	UBERON:0001295	79.06	gold quality
endocervix	UBERON:0000458	73.21	gold quality
uterus	UBERON:0000995	70.76	gold quality
caput epididymis	UBERON:0004358	66.39	gold quality
female reproductive system	UBERON:0000474	60.51	gold quality
sural nerve	UBERON:0015488	60.13	silver quality
anterior cingulate cortex	UBERON:0009835	58.82	gold quality
right frontal lobe	UBERON:0002810	58.37	gold quality
prefrontal cortex	UBERON:0000451	58.09	gold quality
decidua	UBERON:0002450	57.66	gold quality
smooth muscle tissue	UBERON:0001135	56.75	gold quality
body of uterus	UBERON:0009853	56.59	gold quality
oviduct epithelium	UBERON:0004804	55.98	gold quality
Brodmann (1909) area 9	UBERON:0013540	55.18	gold quality
neocortex	UBERON:0001950	55.09	gold quality
upper lobe of lung	UBERON:0008948	54.69	silver quality
frontal cortex	UBERON:0001870	54.66	gold quality
hindlimb stylopod muscle	UBERON:0004252	54.51	gold quality
lower lobe of lung	UBERON:0008949	54.18	silver quality
corpus callosum	UBERON:0002336	54.14	gold quality
fallopian tube	UBERON:0003889	53.90	gold quality
uterine cervix	UBERON:0000002	53.75	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	53.71	gold quality
cerebral cortex	UBERON:0000956	52.72	gold quality
right uterine tube	UBERON:0001302	52.71	gold quality
amygdala	UBERON:0001876	52.48	gold quality
Ammon’s horn	UBERON:0001954	51.35	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	51.10	gold quality
putamen	UBERON:0001874	50.72	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-10287	yes	48.01
E-ANND-3	yes	5.03

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.