MFF-DT

Summary

MFF-DT (MFF divergent transcript, HGNC:41067) is a long non-coding RNA gene on chromosome 2q36.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41067
Approved symbol	MFF-DT
Name	MFF divergent transcript
Location	2q36.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236432
Ensembl biotype	lncRNA
Entrez	654841
RNAcentral	URS000075AC2B — lncRNA, 2516 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 21 — 21 lncRNA

ENST00000396588, ENST00000433324, ENST00000437673, ENST00000439598, ENST00000606119, ENST00000656540, ENST00000656707, ENST00000656771, ENST00000657158, ENST00000657873, ENST00000658093, ENST00000658632, ENST00000660803, ENST00000662009, ENST00000665165, ENST00000665988, ENST00000666788, ENST00000668704, ENST00000669075, ENST00000670070, ENST00000671563

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000396588 — 10 exons

Exon	Start	End
ENSE00001608544	227268628	227268769
ENSE00001650921	227259178	227259283
ENSE00001662827	227245710	227246265
ENSE00001722652	227265875	227265935
ENSE00001747025	227301793	227301974
ENSE00001760171	227264669	227265438
ENSE00001778346	227281704	227281789
ENSE00001782755	227305460	227305655
ENSE00001800300	227279483	227279578
ENSE00002506639	227325168	227325186

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 81.18.

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.18	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.95	gold quality
bone marrow cell	CL:0002092	71.23	silver quality
metanephros cortex	UBERON:0010533	68.31	gold quality
cortical plate	UBERON:0005343	67.54	gold quality
islet of Langerhans	UBERON:0000006	66.52	gold quality
ventricular zone	UBERON:0003053	65.78	gold quality
ganglionic eminence	UBERON:0004023	65.03	gold quality
descending thoracic aorta	UBERON:0002345	64.95	gold quality
ascending aorta	UBERON:0001496	64.76	gold quality
thoracic aorta	UBERON:0001515	64.70	gold quality
prefrontal cortex	UBERON:0000451	63.93	gold quality
sural nerve	UBERON:0015488	63.91	silver quality
right adrenal gland cortex	UBERON:0035827	63.75	gold quality
metanephros	UBERON:0000081	63.69	gold quality
left lobe of thyroid gland	UBERON:0001120	63.48	gold quality
left coronary artery	UBERON:0001626	63.46	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.46	gold quality
left adrenal gland	UBERON:0001234	63.29	gold quality
colonic epithelium	UBERON:0000397	63.22	silver quality
gastrocnemius	UBERON:0001388	63.22	gold quality
pancreas	UBERON:0001264	63.18	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.17	gold quality
left adrenal gland cortex	UBERON:0035825	63.05	gold quality
adrenal tissue	UBERON:0018303	63.01	gold quality
muscle of leg	UBERON:0001383	62.96	gold quality
aorta	UBERON:0000947	62.84	gold quality
thyroid gland	UBERON:0002046	62.77	gold quality
right adrenal gland	UBERON:0001233	62.74	gold quality
adrenal gland	UBERON:0002369	62.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	5.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.