MHENCR

Summary

MHENCR (melanoma highly expressed competing endogenous lncRNA for miR-425 and miR-489, HGNC:53110) is a long non-coding RNA gene on chromosome 20q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53110
Approved symbol	MHENCR
Name	melanoma highly expressed competing endogenous lncRNA for miR-425 and miR-489
Location	20q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232442
Ensembl biotype	lncRNA
Entrez	100505771
RNAcentral	URS00008E398E — lncRNA, 793 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000411579, ENST00000449500, ENST00000685151, ENST00000686481, ENST00000825379, ENST00000825380, ENST00000825381, ENST00000825382, ENST00000825383

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411579 — 2 exons

Exon	Start	End
ENSE00004235585	63628269	63628712
ENSE00004235592	63627209	63627392

Expression profiles

Bgee: expression breadth ubiquitous, 136 present calls, max score 98.69.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 18.1602 / max 386.7451, expressed in 1796 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
185842	14.3149	1760
185841	3.8453	1428

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	98.69	gold quality
left lobe of thyroid gland	UBERON:0001120	96.70	gold quality
right lobe of thyroid gland	UBERON:0001119	96.58	gold quality
thyroid gland	UBERON:0002046	96.25	gold quality
quadriceps femoris	UBERON:0001377	95.93	gold quality
spleen	UBERON:0002106	94.78	gold quality
right uterine tube	UBERON:0001302	93.26	gold quality
right hemisphere of cerebellum	UBERON:0014890	93.16	gold quality
cerebellar hemisphere	UBERON:0002245	92.40	gold quality
cerebellar cortex	UBERON:0002129	92.26	gold quality
cerebellum	UBERON:0002037	92.13	gold quality
cerebellar vermis	UBERON:0004720	91.65	gold quality
lower esophagus mucosa	UBERON:0035834	91.57	gold quality
blood	UBERON:0000178	91.45	gold quality
granulocyte	CL:0000094	91.17	gold quality
metanephros cortex	UBERON:0010533	90.43	gold quality
small intestine Peyer’s patch	UBERON:0003454	89.62	gold quality
pituitary gland	UBERON:0000007	89.51	gold quality
right lung	UBERON:0002167	89.33	gold quality
adenohypophysis	UBERON:0002196	89.02	gold quality
spinal cord	UBERON:0002240	88.77	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	88.75	gold quality
mucosa of transverse colon	UBERON:0004991	88.47	gold quality
amygdala	UBERON:0001876	88.29	gold quality
temporal lobe	UBERON:0001871	88.12	gold quality
substantia nigra	UBERON:0002038	88.03	gold quality
lymph node	UBERON:0000029	87.93	gold quality
Ammon’s horn	UBERON:0001954	87.86	gold quality
apex of heart	UBERON:0002098	87.74	gold quality
prostate gland	UBERON:0002367	87.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.19

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.