MIA2-AS1

Summary

MIA2-AS1 (MIA2 antisense RNA 1, HGNC:55436) is a long non-coding RNA gene on chromosome 14q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55436
Approved symbol	MIA2-AS1
Name	MIA2 antisense RNA 1
Location	14q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258940
Ensembl biotype	lncRNA
Entrez	100288846
RNAcentral	URS000075EB1D — lncRNA, 1377 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000553520, ENST00000605298

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553520 — 2 exons

Exon	Start	End
ENSE00002507084	39266960	39267061
ENSE00002515036	39266420	39266784

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 88.13.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4374 / max 9.5344, expressed in 219 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
143019	0.4374	219

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.42	gold quality
right adrenal gland	UBERON:0001233	71.50	gold quality
right adrenal gland cortex	UBERON:0035827	70.90	gold quality
thymus	UBERON:0002370	70.71	silver quality
left adrenal gland	UBERON:0001234	70.41	gold quality
duodenum	UBERON:0002114	70.39	gold quality
left adrenal gland cortex	UBERON:0035825	69.75	gold quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
adrenal gland	UBERON:0002369	69.32	gold quality
cortical plate	UBERON:0005343	68.13	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	67.07	gold quality
bone marrow cell	CL:0002092	67.03	silver quality
prefrontal cortex	UBERON:0000451	66.71	gold quality
ventricular zone	UBERON:0003053	66.09	gold quality
leukocyte	CL:0000738	64.32	gold quality
monocyte	CL:0000576	64.26	gold quality
temporal lobe	UBERON:0001871	63.98	gold quality
amygdala	UBERON:0001876	63.95	gold quality
granulocyte	CL:0000094	63.91	gold quality
anterior cingulate cortex	UBERON:0009835	63.53	gold quality
ganglionic eminence	UBERON:0004023	63.52	gold quality
skeletal muscle tissue	UBERON:0001134	63.50	gold quality
hypothalamus	UBERON:0001898	63.27	gold quality
frontal cortex	UBERON:0001870	63.16	gold quality
nucleus accumbens	UBERON:0001882	62.49	gold quality
Ammon’s horn	UBERON:0001954	62.47	gold quality
cerebral cortex	UBERON:0000956	62.46	gold quality
islet of Langerhans	UBERON:0000006	62.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.19

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.