MIDEAS-AS1

Summary

MIDEAS-AS1 (MIDEAS antisense RNA 1, HGNC:56194) is a long non-coding RNA gene on chromosome 14q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56194
Approved symbol	MIDEAS-AS1
Name	MIDEAS antisense RNA 1
Location	14q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259065
Ensembl biotype	lncRNA
Entrez	100506476
RNAcentral	URS000075D197 — lncRNA, 996 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000553470, ENST00000556194, ENST00000668116, ENST00000702221

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553470 — 2 exons

Exon	Start	End
ENSE00002456836	73788965	73789116
ENSE00002510311	73802885	73803270

Expression profiles

Bgee: expression breadth ubiquitous, 188 present calls, max score 85.64.

Top tissues by expression

238 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.64	gold quality
gastrocnemius	UBERON:0001388	82.83	gold quality
muscle of leg	UBERON:0001383	82.70	gold quality
hindlimb stylopod muscle	UBERON:0004252	82.57	gold quality
apex of heart	UBERON:0002098	82.38	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.96	gold quality
heart left ventricle	UBERON:0002084	81.25	gold quality
cardiac ventricle	UBERON:0002082	80.64	gold quality
right atrium auricular region	UBERON:0006631	80.47	gold quality
cardiac atrium	UBERON:0002081	80.01	gold quality
heart	UBERON:0000948	78.57	gold quality
buccal mucosa cell	CL:0002336	78.28	silver quality
cardiac muscle of right atrium	UBERON:0003379	77.54	gold quality
left ventricle myocardium	UBERON:0006566	77.28	gold quality
left ovary	UBERON:0002119	76.45	gold quality
putamen	UBERON:0001874	75.71	gold quality
nucleus accumbens	UBERON:0001882	75.43	gold quality
muscle tissue	UBERON:0002385	75.16	gold quality
mucosa of stomach	UBERON:0001199	75.15	gold quality
kidney epithelium	UBERON:0004819	74.95	gold quality
skeletal muscle tissue	UBERON:0001134	74.91	gold quality
right coronary artery	UBERON:0001625	74.66	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	74.66	gold quality
right uterine tube	UBERON:0001302	74.64	gold quality
right adrenal gland cortex	UBERON:0035827	74.44	gold quality
right lobe of liver	UBERON:0001114	74.21	gold quality
right adrenal gland	UBERON:0001233	73.99	gold quality
muscle layer of sigmoid colon	UBERON:0035805	73.98	gold quality
vastus lateralis	UBERON:0001379	73.58	silver quality
caudate nucleus	UBERON:0001873	73.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.60

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD. (PMID:37770991)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.