MIOS-DT

Summary

MIOS-DT (MIOS divergent transcript, HGNC:55187) is a long non-coding RNA gene on chromosome 7p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55187
Approved symbol	MIOS-DT
Name	MIOS divergent transcript
Location	7p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272894
Ensembl biotype	lncRNA
Entrez	101927391
RNAcentral	URS000075EE2C — lncRNA, 2427 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000608807, ENST00000609307, ENST00000609497, ENST00000729942, ENST00000729943, ENST00000729944, ENST00000729945, ENST00000729946, ENST00000729947, ENST00000729948, ENST00000729949, ENST00000729950, ENST00000729951, ENST00000729952, ENST00000729953, ENST00000729954, ENST00000729955, ENST00000729956

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000608807 — 3 exons

Exon	Start	End
ENSE00004029473	7555156	7555189
ENSE00004058041	7564237	7564482
ENSE00004058062	7552447	7552922

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 92.11.

FANTOM5 (CAGE): breadth broad, TPM avg 1.2491 / max 54.2742, expressed in 531 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
82683	1.0042	457
82682	0.1508	54
82681	0.0507	22
82680	0.0435	9

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
body of pancreas	UBERON:0001150	92.11	gold quality
body of stomach	UBERON:0001161	87.50	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.40	gold quality
stomach	UBERON:0000945	85.28	gold quality
fundus of stomach	UBERON:0001160	84.50	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.49	gold quality
gastrocnemius	UBERON:0001388	83.97	gold quality
hindlimb stylopod muscle	UBERON:0004252	83.77	gold quality
right uterine tube	UBERON:0001302	83.72	gold quality
pancreas	UBERON:0001264	83.42	gold quality
muscle of leg	UBERON:0001383	83.06	gold quality
corpus callosum	UBERON:0002336	83.00	gold quality
mucosa of stomach	UBERON:0001199	82.54	gold quality
metanephros cortex	UBERON:0010533	82.52	gold quality
sural nerve	UBERON:0015488	82.06	gold quality
pituitary gland	UBERON:0000007	81.92	gold quality
adenohypophysis	UBERON:0002196	81.27	gold quality
calcaneal tendon	UBERON:0003701	81.14	gold quality
right hemisphere of cerebellum	UBERON:0014890	80.64	gold quality
cortex of kidney	UBERON:0001225	80.22	gold quality
left adrenal gland cortex	UBERON:0035825	80.19	gold quality
right adrenal gland cortex	UBERON:0035827	79.89	gold quality
cerebellar hemisphere	UBERON:0002245	79.80	gold quality
cerebellar cortex	UBERON:0002129	79.76	gold quality
popliteal artery	UBERON:0002250	79.75	gold quality
tibial artery	UBERON:0007610	79.73	gold quality
adult mammalian kidney	UBERON:0000082	79.72	gold quality
left lobe of thyroid gland	UBERON:0001120	79.61	gold quality
cerebellum	UBERON:0002037	79.61	gold quality
thyroid gland	UBERON:0002046	79.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	9.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.