MIR1910

Summary

MIR1910 (microRNA 1910, HGNC:35394) is a microRNA gene on chromosome 16q24.1.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100302261 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:35394
Approved symbol	MIR1910
Name	microRNA 1910
Location	16q24.1
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-1910
Ensembl gene	ENSG00000283416
Ensembl biotype	miRNA
Entrez	100302261
RNAcentral	URS000075EEF1 — miRNA, 80 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000636955

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000636955 — 1 exons

Exon	Start	End
ENSE00003800984	85741621	85741700

Expression profiles

Bgee: expression breadth broad, 63 present calls, max score 79.86.

Top tissues by expression

63 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow	UBERON:0002371	79.86	gold quality
placenta	UBERON:0001987	78.93	gold quality
blood	UBERON:0000178	77.28	gold quality
monocyte	CL:0000576	77.01	gold quality
adrenal tissue	UBERON:0018303	75.25	gold quality
rectum	UBERON:0001052	73.60	gold quality
stomach	UBERON:0000945	73.01	gold quality
gastrocnemius	UBERON:0001388	72.42	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.64	gold quality
lung	UBERON:0002048	71.36	gold quality
amygdala	UBERON:0001876	71.23	gold quality
lymph node	UBERON:0000029	70.88	gold quality
heart	UBERON:0000948	70.78	gold quality
adult mammalian kidney	UBERON:0000082	70.33	gold quality
body of stomach	UBERON:0001161	69.97	gold quality
heart left ventricle	UBERON:0002084	69.93	gold quality
endometrium	UBERON:0001295	69.10	gold quality
subcutaneous adipose tissue	UBERON:0002190	68.27	gold quality
adrenal gland	UBERON:0002369	67.76	gold quality
minor salivary gland	UBERON:0001830	67.71	gold quality
apex of heart	UBERON:0002098	67.27	gold quality
Ammon’s horn	UBERON:0001954	66.08	gold quality
ascending aorta	UBERON:0001496	65.76	gold quality
lower esophagus muscularis layer	UBERON:0035833	65.65	gold quality
tibial artery	UBERON:0007610	65.62	gold quality
esophagus	UBERON:0001043	65.37	gold quality
transverse colon	UBERON:0001157	65.26	gold quality
putamen	UBERON:0001874	65.22	gold quality
esophagus mucosa	UBERON:0002469	65.21	gold quality
adipose tissue	UBERON:0001013	65.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• LINC00174 contributed to colorectal cancer progression by regulating miR-1910-3p/TAZ signal pathway. (PMID:29729381)
• Exosomal miR-1910-3p promotes proliferation, metastasis, and autophagy of breast cancer cells by targeting MTMR3 and activating the NF-kappaB signaling pathway. (PMID:32531321)
• Is microRNA 1910-3p (miR-1910-3p) a really distinctive marker for psoriasis? (PMID:33356031)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.