MIR200CHG

Summary

MIR200CHG (MIR200C and MIR141 host gene, HGNC:53161) is a long non-coding RNA gene on chromosome 12p13.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53161
Approved symbol	MIR200CHG
Name	MIR200C and MIR141 host gene
Location	12p13.31
Locus type	RNA, long non-coding
Status	Approved
Aliases	U47924.27
Ensembl gene	ENSG00000257084
Ensembl biotype	lncRNA
Entrez	105369635
RNAcentral	URS0000A7645A — lncRNA, 366 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000537269, ENST00000732834, ENST00000732835, ENST00000732836, ENST00000732837, ENST00000732838, ENST00000732839, ENST00000732840

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000537269 — 2 exons

Exon	Start	End
ENSE00004063573	6964201	6964458
ENSE00004063578	6963126	6963348

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 95.98.

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
olfactory segment of nasal mucosa	UBERON:0005386	95.98	gold quality
pituitary gland	UBERON:0000007	93.68	gold quality
mucosa of transverse colon	UBERON:0004991	92.83	gold quality
adenohypophysis	UBERON:0002196	92.29	gold quality
body of pancreas	UBERON:0001150	91.81	gold quality
right uterine tube	UBERON:0001302	91.16	gold quality
left lobe of thyroid gland	UBERON:0001120	90.40	gold quality
pancreas	UBERON:0001264	89.87	gold quality
right lobe of thyroid gland	UBERON:0001119	89.52	gold quality
thyroid gland	UBERON:0002046	89.51	gold quality
prostate gland	UBERON:0002367	88.98	gold quality
minor salivary gland	UBERON:0001830	88.42	gold quality
saliva-secreting gland	UBERON:0001044	88.39	gold quality
islet of Langerhans	UBERON:0000006	87.21	gold quality
fundus of stomach	UBERON:0001160	85.56	gold quality
duodenum	UBERON:0002114	84.64	gold quality
body of stomach	UBERON:0001161	83.71	gold quality
esophagus mucosa	UBERON:0002469	82.97	gold quality
rectum	UBERON:0001052	82.57	gold quality
transverse colon	UBERON:0001157	82.55	gold quality
stomach	UBERON:0000945	81.62	gold quality
cortex of kidney	UBERON:0001225	81.34	gold quality
skin of leg	UBERON:0001511	81.30	gold quality
zone of skin	UBERON:0000014	81.25	gold quality
skin of abdomen	UBERON:0001416	81.21	gold quality
metanephros cortex	UBERON:0010533	80.63	gold quality
lower esophagus mucosa	UBERON:0035834	80.55	gold quality
granulocyte	CL:0000094	80.15	gold quality
colonic epithelium	UBERON:0000397	78.76	gold quality
small intestine	UBERON:0002108	77.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	16.52

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation. (PMID:38065939)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.