MIR302CHG
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Summary
MIR302CHG (miR-302/367 cluster host gene, HGNC:41070) is a long non-coding RNA gene on chromosome 4q25.
Predicted to be involved in miRNA-mediated post-transcriptional gene silencing. Predicted to be part of RISC complex.
Source: NCBI Gene 109864269 — RefSeq curated summary.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:41070 |
| Approved symbol | MIR302CHG |
| Name | miR-302/367 cluster host gene |
| Location | 4q25 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000249532 |
| Ensembl biotype | lncRNA |
| Entrez | 109864269 |
| RNAcentral | URS0000ABD8BC — lncRNA, 414 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 11 — 11 lncRNA
ENST00000505215, ENST00000505632, ENST00000509938, ENST00000510655, ENST00000688371, ENST00000691790, ENST00000731548, ENST00000731549, ENST00000731550, ENST00000731551, ENST00000731552
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000505215 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00003986151 | 112646719 | 112646968 |
| ENSE00004061090 | 112648654 | 112648788 |
Expression profiles
Bgee: expression breadth ubiquitous, 131 present calls, max score 89.53.
FANTOM5 (CAGE): breadth tissue_specific, TPM avg 28.1028 / max 2826.9638, expressed in 146 samples.
FANTOM5 promoters (3 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 53662 | 25.5819 | 143 |
| 203313 | 2.4210 | 111 |
| 53663 | 0.0999 | 50 |
Top tissues by expression
131 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 89.53 | gold quality |
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 83.71 | gold quality |
| sural nerve | UBERON:0015488 | 81.09 | gold quality |
| monocyte | CL:0000576 | 76.22 | gold quality |
| colonic epithelium | UBERON:0000397 | 75.27 | gold quality |
| cortical plate | UBERON:0005343 | 74.28 | gold quality |
| bone marrow | UBERON:0002371 | 73.02 | gold quality |
| ventricular zone | UBERON:0003053 | 71.04 | gold quality |
| bone marrow cell | CL:0002092 | 69.62 | gold quality |
| calcaneal tendon | UBERON:0003701 | 69.61 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 69.36 | gold quality |
| muscle tissue | UBERON:0002385 | 68.81 | gold quality |
| blood | UBERON:0000178 | 67.66 | gold quality |
| endometrium | UBERON:0001295 | 66.90 | gold quality |
| adrenal tissue | UBERON:0018303 | 66.71 | gold quality |
| granulocyte | CL:0000094 | 66.52 | gold quality |
| ganglionic eminence | UBERON:0004023 | 66.42 | gold quality |
| smooth muscle tissue | UBERON:0001135 | 66.15 | gold quality |
| lymph node | UBERON:0000029 | 65.05 | gold quality |
| rectum | UBERON:0001052 | 64.40 | gold quality |
| thoracic mammary gland | UBERON:0005200 | 63.90 | gold quality |
| mucosa of stomach | UBERON:0001199 | 63.70 | gold quality |
| skin of abdomen | UBERON:0001416 | 63.18 | gold quality |
| vermiform appendix | UBERON:0001154 | 63.05 | gold quality |
| right lung | UBERON:0002167 | 62.59 | gold quality |
| primary visual cortex | UBERON:0002436 | 62.44 | gold quality |
| duodenum | UBERON:0002114 | 62.37 | gold quality |
| corpus callosum | UBERON:0002336 | 62.22 | gold quality |
| myometrium | UBERON:0001296 | 62.12 | gold quality |
| placenta | UBERON:0001987 | 61.81 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 2.78 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): microcephalic primordial dwarfism, Alazami type