MIR3142HG

Summary

MIR3142HG (MIR3142 host gene, HGNC:51944) is a long non-coding RNA gene on chromosome 5q33.3.

Predicted to be involved in miRNA-mediated post-transcriptional gene silencing. Predicted to be part of RISC complex.

Source: NCBI Gene 107075116 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51944
Approved symbol	MIR3142HG
Name	MIR3142 host gene
Location	5q33.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000253522
Ensembl biotype	lncRNA
Entrez	107075116
RNAcentral	URS00008E3A4A — lncRNA, 2331 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000517927, ENST00000642173, ENST00000770454, ENST00000770455, ENST00000770456, ENST00000770457, ENST00000770458, ENST00000770459

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000517927 — 2 exons

Exon	Start	End
ENSE00002103277	160485299	160487426
ENSE00004132528	160468131	160468440

Expression profiles

Bgee: expression breadth ubiquitous, 166 present calls, max score 93.16.

FANTOM5 (CAGE): breadth broad, TPM avg 25.6243 / max 1473.2232, expressed in 716 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
59910	25.1183	702
59911	0.2640	135
59915	0.2421	130

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	93.16	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.54	gold quality
palpebral conjunctiva	UBERON:0001812	74.28	gold quality
minor salivary gland	UBERON:0001830	74.27	gold quality
epithelial cell of pancreas	CL:0000083	73.23	gold quality
lymph node	UBERON:0000029	72.76	gold quality
vermiform appendix	UBERON:0001154	72.65	gold quality
saliva-secreting gland	UBERON:0001044	72.42	gold quality
mouth mucosa	UBERON:0003729	70.69	gold quality
rectum	UBERON:0001052	68.96	gold quality
granulocyte	CL:0000094	68.71	gold quality
cartilage tissue	UBERON:0002418	68.02	silver quality
tendon of biceps brachii	UBERON:0008188	67.44	gold quality
epithelium of nasopharynx	UBERON:0001951	66.83	silver quality
caecum	UBERON:0001153	66.67	gold quality
spleen	UBERON:0002106	66.41	gold quality
tonsil	UBERON:0002372	66.14	gold quality
leukocyte	CL:0000738	66.07	gold quality
nasal cavity mucosa	UBERON:0001826	65.93	gold quality
monocyte	CL:0000576	65.90	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	65.55	gold quality
mucosa of transverse colon	UBERON:0004991	64.34	gold quality
mucosa of stomach	UBERON:0001199	63.80	gold quality
gall bladder	UBERON:0002110	63.10	gold quality
myocardium	UBERON:0002349	62.88	gold quality
buccal mucosa cell	CL:0002336	62.62	gold quality
cauda epididymis	UBERON:0004360	62.15	gold quality
sural nerve	UBERON:0015488	61.90	silver quality
trabecular bone tissue	UBERON:0002483	61.69	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	61.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.10

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Polymorphisms in MIR3142HG are associated with susceptibility to Glioma. (PMID:31513017)
• MIR3142HG promotes lipopolysaccharide-induced acute lung injury by regulating miR-450b-5p/HMGB1 axis. (PMID:34338955)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.