MIR3152

Summary

MIR3152 (microRNA 3152, HGNC:38379) is a microRNA gene on chromosome 9p22.1.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100422869 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38379
Approved symbol	MIR3152
Name	microRNA 3152
Location	9p22.1
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3152
Ensembl gene	ENSG00000264638
Ensembl biotype	miRNA
Entrez	100422869
RNAcentral	URS000075D6B9 — ncRNA, 74 nt, 3 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000579801

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000579801 — 1 exons

Exon	Start	End
ENSE00002711601	18573306	18573379

Expression profiles

Bgee: expression breadth broad, 37 present calls, max score 80.59.

Top tissues by expression

37 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	80.59	gold quality
lung	UBERON:0002048	80.53	gold quality
adrenal tissue	UBERON:0018303	78.48	gold quality
heart	UBERON:0000948	77.94	gold quality
monocyte	CL:0000576	75.89	gold quality
calcaneal tendon	UBERON:0003701	75.34	gold quality
liver	UBERON:0002107	74.92	gold quality
gastrocnemius	UBERON:0001388	69.75	gold quality
stomach	UBERON:0000945	68.64	gold quality
intestine	UBERON:0000160	68.22	gold quality
myometrium	UBERON:0001296	67.70	gold quality
body of stomach	UBERON:0001161	67.57	gold quality
right adrenal gland cortex	UBERON:0035827	65.49	gold quality
prostate gland	UBERON:0002367	65.43	gold quality
omental fat pad	UBERON:0010414	64.78	gold quality
left adrenal gland	UBERON:0001234	64.55	gold quality
ascending aorta	UBERON:0001496	64.26	gold quality
descending thoracic aorta	UBERON:0002345	64.19	gold quality
lower esophagus muscularis layer	UBERON:0035833	64.17	gold quality
transverse colon	UBERON:0001157	64.08	gold quality
endocervix	UBERON:0000458	64.04	gold quality
subcutaneous adipose tissue	UBERON:0002190	64.02	gold quality
skin of abdomen	UBERON:0001416	63.90	gold quality
skin of leg	UBERON:0001511	63.30	gold quality
body of uterus	UBERON:0009853	63.10	gold quality
tibial nerve	UBERON:0001323	62.52	gold quality
esophagus mucosa	UBERON:0002469	62.50	gold quality
left uterine tube	UBERON:0001303	61.91	gold quality
small intestine Peyer’s patch	UBERON:0003454	61.80	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	61.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.