MIR3155A

Summary

MIR3155A (microRNA 3155a, HGNC:38245) is a microRNA gene on chromosome 10p15.1.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100422989 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38245
Approved symbol	MIR3155A
Name	microRNA 3155a
Location	10p15.1
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3155
Ensembl gene	ENSG00000263628
Ensembl biotype	miRNA
Entrez	100422989
RNAcentral	URS000075C9CE — miRNA, 82 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000577482

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000577482 — 1 exons

Exon	Start	End
ENSE00002703516	6152196	6152277

Expression profiles

Bgee: expression breadth broad, 79 present calls, max score 82.60.

Top tissues by expression

79 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
calcaneal tendon	UBERON:0003701	82.60	gold quality
adrenal tissue	UBERON:0018303	80.74	gold quality
blood	UBERON:0000178	77.59	gold quality
liver	UBERON:0002107	77.47	gold quality
placenta	UBERON:0001987	76.89	gold quality
monocyte	CL:0000576	76.77	gold quality
kidney	UBERON:0002113	76.24	gold quality
bone marrow	UBERON:0002371	74.89	gold quality
muscle of leg	UBERON:0001383	74.19	gold quality
urinary bladder	UBERON:0001255	74.13	gold quality
granulocyte	CL:0000094	73.51	gold quality
gastrocnemius	UBERON:0001388	72.81	gold quality
stomach	UBERON:0000945	72.80	gold quality
ectocervix	UBERON:0012249	72.67	gold quality
sural nerve	UBERON:0015488	71.64	gold quality
heart	UBERON:0000948	68.68	gold quality
endometrium	UBERON:0001295	68.37	gold quality
right atrium auricular region	UBERON:0006631	68.35	gold quality
body of uterus	UBERON:0009853	68.15	gold quality
heart left ventricle	UBERON:0002084	67.98	gold quality
right lobe of liver	UBERON:0001114	67.95	gold quality
body of stomach	UBERON:0001161	67.84	gold quality
body of pancreas	UBERON:0001150	67.46	gold quality
tibial artery	UBERON:0007610	67.25	gold quality
multicellular organism	UBERON:0000468	67.15	gold quality
caudate nucleus	UBERON:0001873	66.97	gold quality
putamen	UBERON:0001874	66.44	gold quality
lung	UBERON:0002048	66.30	gold quality
thoracic aorta	UBERON:0001515	66.16	gold quality
ascending aorta	UBERON:0001496	66.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.