MIR3160-1

Summary

MIR3160-1 (microRNA 3160-1, HGNC:38197) is a microRNA gene on chromosome 11p11.2.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100422827 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38197
Approved symbol	MIR3160-1
Name	microRNA 3160-1
Location	11p11.2
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3160-1
Ensembl gene	ENSG00000265014
Ensembl biotype	miRNA
Entrez	100422827
RNAcentral	URS000075E12E — miRNA, 85 nt, 4 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000577972

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000577972 — 1 exons

Exon	Start	End
ENSE00002715137	46451805	46451889

Expression profiles

Bgee: expression breadth broad, 20 present calls, max score 78.40.

Top tissues by expression

20 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
stomach	UBERON:0000945	78.40	gold quality
blood	UBERON:0000178	78.39	gold quality
subcutaneous adipose tissue	UBERON:0002190	75.32	gold quality
anterior cingulate cortex	UBERON:0009835	74.69	gold quality
tibial artery	UBERON:0007610	73.14	gold quality
colon	UBERON:0001155	73.01	gold quality
heart	UBERON:0000948	72.80	gold quality
spleen	UBERON:0002106	72.74	gold quality
calcaneal tendon	UBERON:0003701	72.22	gold quality
thoracic aorta	UBERON:0001515	68.86	gold quality
skin of abdomen	UBERON:0001416	66.15	gold quality
tibial nerve	UBERON:0001323	63.57	gold quality
corpus callosum	UBERON:0002336	63.15	gold quality
caudate nucleus	UBERON:0001873	62.57	gold quality
pituitary gland	UBERON:0000007	59.98	gold quality
upper lobe of left lung	UBERON:0008952	59.40	gold quality
omental fat pad	UBERON:0010414	59.17	gold quality
minor salivary gland	UBERON:0001830	55.98	gold quality
right frontal lobe	UBERON:0002810	54.52	gold quality
cerebellar hemisphere	UBERON:0002245	51.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.