MIR3160-2

Summary

MIR3160-2 (microRNA 3160-2, HGNC:38192) is a microRNA gene on chromosome 11p11.2.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100422825 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38192
Approved symbol	MIR3160-2
Name	microRNA 3160-2
Location	11p11.2
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3160-2
Ensembl gene	ENSG00000283497
Ensembl biotype	miRNA
Entrez	100422825
RNAcentral	URS000075D29F — miRNA, 81 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000637870

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000637870 — 1 exons

Exon	Start	End
ENSE00003801132	46451807	46451887

Expression profiles

Bgee: expression breadth tissue_specific, 4 present calls, max score 73.07.

Top tissues by expression

4 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skin of abdomen	UBERON:0001416	73.07	gold quality
cerebellar hemisphere	UBERON:0002245	58.31	gold quality
upper lobe of left lung	UBERON:0008952	55.85	gold quality
left testis	UBERON:0004533	48.61	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.