MIR3164

Summary

MIR3164 (microRNA 3164, HGNC:38288) is a microRNA gene on chromosome 11q13.3.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100422846 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38288
Approved symbol	MIR3164
Name	microRNA 3164
Location	11q13.3
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3164
Ensembl gene	ENSG00000265539
Ensembl biotype	miRNA
Entrez	100422846
RNAcentral	URS000075E7C6 — ncRNA, 83 nt, 3 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000581178

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000581178 — 1 exons

Exon	Start	End
ENSE00002716588	69083176	69083258

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 88.24.

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	88.24	gold quality
lower esophagus muscularis layer	UBERON:0035833	87.18	gold quality
lower esophagus	UBERON:0013473	87.04	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	86.57	gold quality
smooth muscle tissue	UBERON:0001135	83.90	gold quality
bone marrow	UBERON:0002371	83.83	gold quality
right coronary artery	UBERON:0001625	83.56	gold quality
muscle layer of sigmoid colon	UBERON:0035805	83.52	gold quality
adrenal tissue	UBERON:0018303	82.88	gold quality
body of uterus	UBERON:0009853	81.16	gold quality
left uterine tube	UBERON:0001303	80.81	gold quality
vermiform appendix	UBERON:0001154	80.45	gold quality
muscle of leg	UBERON:0001383	80.19	gold quality
tibial artery	UBERON:0007610	79.92	gold quality
heart left ventricle	UBERON:0002084	79.86	gold quality
popliteal artery	UBERON:0002250	79.83	gold quality
urinary bladder	UBERON:0001255	79.68	gold quality
mucosa of stomach	UBERON:0001199	79.60	gold quality
esophagus	UBERON:0001043	79.56	gold quality
colon	UBERON:0001155	79.49	gold quality
myometrium	UBERON:0001296	79.32	gold quality
fundus of stomach	UBERON:0001160	79.00	gold quality
gastrocnemius	UBERON:0001388	78.90	gold quality
heart	UBERON:0000948	78.00	gold quality
placenta	UBERON:0001987	76.78	gold quality
stomach	UBERON:0000945	76.72	gold quality
body of stomach	UBERON:0001161	76.53	gold quality
left coronary artery	UBERON:0001626	76.30	gold quality
transverse colon	UBERON:0001157	76.26	gold quality
fallopian tube	UBERON:0003889	76.22	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.