MIR3167

Summary

MIR3167 (microRNA 3167, HGNC:38242) is a microRNA gene on chromosome 11q24.2.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100422918 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38242
Approved symbol	MIR3167
Name	microRNA 3167
Location	11q24.2
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3167
Ensembl gene	ENSG00000266215
Ensembl biotype	miRNA
Entrez	100422918
RNAcentral	URS000075A4F3 — miRNA, 85 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000579623

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000579623 — 1 exons

Exon	Start	End
ENSE00002700762	126988458	126988542

Expression profiles

Bgee: expression breadth broad, 39 present calls, max score 89.68.

Top tissues by expression

39 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	89.68	gold quality
kidney	UBERON:0002113	84.13	gold quality
monocyte	CL:0000576	83.65	gold quality
omental fat pad	UBERON:0010414	76.52	gold quality
calcaneal tendon	UBERON:0003701	72.13	gold quality
skin of leg	UBERON:0001511	70.61	gold quality
islet of Langerhans	UBERON:0000006	68.86	gold quality
right atrium auricular region	UBERON:0006631	68.41	gold quality
heart	UBERON:0000948	67.49	gold quality
liver	UBERON:0002107	67.47	gold quality
lower esophagus muscularis layer	UBERON:0035833	66.94	gold quality
Brodmann (1909) area 9	UBERON:0013540	65.94	gold quality
stomach	UBERON:0000945	65.66	gold quality
transverse colon	UBERON:0001157	65.62	gold quality
minor salivary gland	UBERON:0001830	65.17	gold quality
Ammon’s horn	UBERON:0001954	65.15	gold quality
brain	UBERON:0000955	65.11	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	64.90	gold quality
anterior cingulate cortex	UBERON:0009835	64.73	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	64.46	gold quality
subcutaneous adipose tissue	UBERON:0002190	64.45	gold quality
muscle layer of sigmoid colon	UBERON:0035805	64.41	gold quality
left coronary artery	UBERON:0001626	64.28	gold quality
colon	UBERON:0001155	64.02	gold quality
nucleus accumbens	UBERON:0001882	63.79	gold quality
amygdala	UBERON:0001876	63.23	gold quality
right ovary	UBERON:0002118	62.86	gold quality
caudate nucleus	UBERON:0001873	62.82	gold quality
right frontal lobe	UBERON:0002810	62.44	gold quality
right hemisphere of cerebellum	UBERON:0014890	61.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.16

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• FOXD1-AS1 promotes malignant behaviours of prostate cancer cells via the miR-3167/YWHAZ axis. (PMID:34674391)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.