MIR3201

Summary

MIR3201 (microRNA 3201, HGNC:38235) is a microRNA gene on chromosome 22q13.32.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Source: NCBI Gene 100422916 — RefSeq curated summary.

At a glance

• Gene type: non-coding (miRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38235
Approved symbol	MIR3201
Name	microRNA 3201
Location	22q13.32
Locus type	RNA, micro
Status	Approved
Aliases	hsa-mir-3201
Ensembl gene	ENSG00000266508
Ensembl biotype	miRNA
Entrez	100422916
RNAcentral	URS000075A7FD — miRNA, 52 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 miRNA

ENST00000578320

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000578320 — 1 exons

Exon	Start	End
ENSE00002687097	48274364	48274415

Expression profiles

Bgee: expression breadth tissue_specific, 4 present calls, max score 71.79.

Top tissues by expression

4 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
caudate nucleus	UBERON:0001873	71.79	gold quality
right frontal lobe	UBERON:0002810	67.79	gold quality
right testis	UBERON:0004534	50.15	gold quality
left testis	UBERON:0004533	48.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Binding efficiency of MIR3201 is associated with severity of coronary artery disease. (PMID:25034063)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.