MIR325HG

Summary

MIR325HG (MIR325 host gene, HGNC:50346) is a long non-coding RNA gene on chromosome Xq13.3-q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50346
Approved symbol	MIR325HG
Name	MIR325 host gene
Location	Xq13.3-q21.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	MIR384HG
Ensembl gene	ENSG00000280870
Ensembl biotype	lncRNA
Entrez	101928469
RNAcentral	URS00007E4186 — lncRNA, 1105 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000626742, ENST00000626832, ENST00000626846, ENST00000627687, ENST00000627760, ENST00000629133, ENST00000629945, ENST00000630388, ENST00000630856, ENST00000658368, ENST00000671589, ENST00000783867, ENST00000783868, ENST00000783869, ENST00000783870, ENST00000783871, ENST00000783872

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000626742 — 4 exons

Exon	Start	End
ENSE00003767414	77014227	77014502
ENSE00003768899	76658796	76658865
ENSE00003770035	76692967	76693087
ENSE00003774063	77007276	77007380

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 77.09.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.6766 / max 81.3311, expressed in 178 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
199784	0.5396	169
199783	0.1106	61
199785	0.0264	8

Top tissues by expression

111 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	77.09	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.83	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.86	gold quality
hypothalamus	UBERON:0001898	68.66	gold quality
substantia nigra	UBERON:0002038	67.75	gold quality
ventricular zone	UBERON:0003053	65.09	gold quality
ganglionic eminence	UBERON:0004023	64.91	gold quality
cortical plate	UBERON:0005343	64.62	gold quality
prefrontal cortex	UBERON:0000451	64.27	gold quality
sural nerve	UBERON:0015488	63.74	silver quality
calcaneal tendon	UBERON:0003701	61.88	gold quality
popliteal artery	UBERON:0002250	61.38	gold quality
tibial artery	UBERON:0007610	61.37	gold quality
tonsil	UBERON:0002372	61.04	silver quality
skeletal muscle tissue	UBERON:0001134	60.95	silver quality
Ammon’s horn	UBERON:0001954	60.21	gold quality
frontal cortex	UBERON:0001870	59.83	gold quality
descending thoracic aorta	UBERON:0002345	59.60	gold quality
superior frontal gyrus	UBERON:0002661	59.55	gold quality
amygdala	UBERON:0001876	59.48	gold quality
temporal lobe	UBERON:0001871	59.40	gold quality
thoracic aorta	UBERON:0001515	59.25	gold quality
ascending aorta	UBERON:0001496	59.20	gold quality
cerebral cortex	UBERON:0000956	58.69	gold quality
anterior cingulate cortex	UBERON:0009835	57.71	gold quality
brain	UBERON:0000955	57.66	gold quality
putamen	UBERON:0001874	57.33	gold quality
primary visual cortex	UBERON:0002436	56.91	gold quality
Brodmann (1909) area 9	UBERON:0013540	56.90	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	56.27	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-HCAD-25	yes	10.86
E-ANND-3	yes	3.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.